Marilyn J. Hammer,
Oncology, Immunology, Glucose Metabolism
The purpose of this mixed methods study is to describe the self-care behaviors of adult/older adult patients with cancer who concurrently have DM and/or CVD and identify factors that facilitate or impede self-care.
To address the significant problem of infections in patients with cancer, the aims of this study are to determine the correlations between glycemic status and infection rates, evaluate three of the potential contributors to malglycemia, and to enhance understanding of immune function under the stress of malignancies, evaluate proinflammatory cytokine expression in comparison to glycemic status among autologous HCT recipients. Findings from this study can lead to nursing-centric interventions for better glycemic control as a novel approach to better infection control among HCT recipients and may be translatable to other populations of patients with cancer and other chronic conditions.
The major goals of this sub-study project are to evaluate glycosylated hemoglobin in patients with cancer and compare levels to their symptom severity and geneic/genomic markers from the main study, Symptom Clusters in Oncology Patients Receiving Chemotherapy (UCSF PIs: Miaskowski and Aouizerat; NYU PIs: Schmidt and Cartwright).