- Professional overview
Dr. Anastasi is one of the country's leading clinical scientists in the area of symptom management. Dr. Anastasi was formerly the Helen F. Pettit Endowed Professor at Columbia University and Director of the Center for AIDS Research and Integrative Therapies in Primary Care Program. Further, she is an outstanding teacher and has received recognition and acclaim through her receipt of the Columbia University Presidential Teaching Award. Dr. Anastasi served on the Advisory Board for the Institute of Medicine’s (IOM) report on The Use of Complementary and Alternative Medicine by the American Public. She is also the principal investigator of several clinical trials funded by the National Institutes of Health (NIH). Dr. Anastasi is a licensed acupuncturist and a Diplomate from the NCCAOM. Dr. Anastasi authored and developed the Herbs, Nutraceuticals and Dietary Supplements© graduate program funded by the Health Resources and Services Administration (HRSA). She has published extensively in the area of symptom management using non-invasive interventions and has received numerous awards for her contributions and expertise in acupuncture and symptom management research.
DrNP, Nursing, Columbia University School of NursingOriental Medicine/ Acupuncture, New York College for Wholistic Health, Education & ResearchPhD, Nursing, Adelphi UniversityMA, Nursing, New York UniversityBSN, Nursing, Wagner College
- Honors and awards
Distinguished Alumni Award in Research, Columbia University (2015)Dedicated Service and Appreciation Certificate for Serving as a NIH Study Section Reviewer (2014)Distinguished Alumni Fellow Award, Wagner College (2014)Research Article of the Year Award: Association of Nurses in AIDS Care, 26th Annual Meeting (2013)Distinguished Researcher Award, Eastern Nursing Research Society (2011)Columbia University Presidential Teaching Award (2007)Distinguished Researcher Award, Foundation of the New York State Nurses Association (2003)The Traditional Chinese Medicine World Foundation, Building Bridges of Integration for Traditional Chinese Medicine, Award for research titled, “Acupuncture for Chronic Nausea in HIV.” (2003)Researcher Recognition Award, Association of Nurses in AIDS Care (2002)Sixth Annual Presidential Columbia University Teaching Award – Finalist (2001)President’s Distinguished Alumnus Award, for Distinguished Service in HIV/AIDS Research and Integrating the Principles of Traditional Chinese Medicine with Biomedical Treatment Approaches, New York College of Wholistic Education and Research (2000)Outstanding Clinical Article of the Year Award: Association of Nurses in AIDS Care, National Meeting (1999)Diplomate of Acupuncture, National Commission for Acupuncture and Oriental Medicine (1998)Excellence in Acupuncture Award, New York College of Wholistic Health Education and Research (1997)Fellow of the American Academy of Nursing (FAAN) (1997)
Non-communicable diseaseInfectious diseaseWomen's healthPrimary careGlobalAdult healthPalliative careComplementary/integrative health
- Professional membership
AIDS Treatment Data Network: Former Board of DirectorsAmerican Academy of Nursing: FellowAmerican Academy of Nurse PractitionersAmerican Holistic Nurses AssociationAmerican Nurses AssociationAmerican Society for Parenteral & Enteral NutritionAmerican Society for Reproductive MedicineAssociation of Nurses in AIDS CareAssociation for Reproductive Health PractitionersEastern Nursing Research SocietyNational Certification Commission for Acupuncture and Oriental Medicine: DiplomatNew York State Nurses AssociationNew York State Acupuncture AssociationOncology Nursing SocietyRESOLVE: The National Infertility AssociationSigma Theta TauSociety of Gastroenterology Nurses and Associates
Addressing the Role of Food in Irritable Bowel Syndrome Symptom ManagementCapili, B, Anastasi, J.K. & Chang, M. (2016). Journal for Nurse Practitioners,
A clinical update: Non-Celiac gluten sensitivity—Is it really the gluten?Capili, B, Anastasi, J.K. & Chang, M. (2014). Journal for Nurse Practitioners, 10, 9, 666-673,
Barriers and facilitators to engagement in lifestyle interventions among individuals with HIVCapili, B, Anastasi, Chang, M, & Ogedegbe, O (2014). JANAC, 25(5), 450-457,
HIV Peripheral Neuropathy and Foot Care ManagementAnastasi, J.K., Capili, B. & Chang, M (2014). American Journal of Nursing, 113, 12, 34-40,
Tongue inspection in TCM: Observations in a study sample of patients living with HIVAnastasi, J.K., Chang, M., Quinn, J, Capili, B (2014). Medical Acupuncture, 26(1), 15-22,
Acu/Moxa for distal sensory peripheral neuropathy in HIV: A randomized control pilot studyAnastasi, J.K., Capili, B., McMahon, D., & Scully, C. (2013). Journal of Association of Nurses in AIDS Care, 24, 3, 268-275,
Exploratory Study: Evaluating the Effects of Fish Oil and Controlled Diet to Reduce Triglyceride Levels in HIVCapili, B. & Anastasi, J.K. (2013). Journal of the Association of Nurses in AIDS Care,
Managing of irritable bowel syndromeAnastasi, J.K., Capili, B. & Chang, M. (2013). American Journal of Nursing, 113, 7, 38-48,
The treatment of Constipation-Predominant Irritable Bowel Syndrome with Acupuncture and Moxibustion: A Case ReportAnastasi, J.K. & Capili, B. (2012). Journal of Chinese Medicine, 99, 70-73,
Use of Complementary /Alternative Medicines and Supplements by Mexican-Origin Patients in a US-Mexico Border HIV ClinicShedlin, M., Anastasi, JK, Decena, CU, Rivera, J, Beltran, O & Smith, K. (2012). JANAC,
Herbal Supplements: Talking with your PatientsAnastasi, J.K., Chang, M., & Capili, B. (2011). The Journal for Nurse Practitioners, 7, 29-35, 10.1016/j.nurpra.2010.06.004
Traditional Chinese Medicine and Human Immunodeficiency Virus Related Neuropathy: A Case ReportAnastasi, J.K., Chang, M., Capili, B, Dawes, N (2011). Australian Journal of Acupuncture and Chinese Medicine, 94, 15-19,
Traditional Chinese medicine and human immunodeficiency virus-associated neuropathyAnastasi, J.K., Chang, M., Capili, B., & Dawes, N. (2011). Journal of Chinese Medicine, 16-20,
Peripheral neuropathy is one of the most common neurological complications of human immunodeficiency virus (HIV) infection and continues to impact people living with HIV/AIDS. The pain associated with peripheral neuropathy can be severe and debilitating. Most pharmacological agents are inadequate in symptom management and are accompanied by adverse side-effects. Acupuncture and moxibustion offer treatment approaches that can reduce HIV symptoms and/or the side-effects of anti-retroviral therapy and improve patients' quality of life.
Treatment of HIV Associated Neuropathy with Acupuncture and MoxibustionAnastasi, J.K., Chang, M., & Capili, B. (2011). Journal of Chinese Medicine, 5(2), 37-40,
Acupuncture and Moxibustion RCT for Distal Symmetric Peripheral Neuropathy in HIV/AIDS: Rationale, Design, Methods, Procedures and FeasibilityAnastasi, J., Capili, B., Dawes, N., & Hammerschlag, R. (2010). European Journal of Chinese Medicine, 6(4), 40-52,
Acupuncture/moxibustion RCT for distal sensory peripheral neuropathy in HIV/AIDS: Rationale, design, methods, procedures and logisticsAnastasi, J.K., Capili, B., Chung, A.M., & Hammerschlag, R. (2010). European Journal of Chinese Medicine, 6, 40-52,
Distal sensory peripheral neuropathy is a common neurological complication experienced by people living with the human immunodeficiency virus (HIV). Traditional Chinese medicine (TCM) may offer effective interventions in the management of its symptoms. To improve the quality and transparency of reporting acupuncture clinical trials, the Consolidated Standards of Reporting Trials (CONSORT) guidelines were developed in 1996 and the Standards for Reporting Interventions in Controlled Trials of Acupuncture (STRICTA) recommendations were introduced in 2001. Incorporating international guidelines, this paper describes the development of a RCT including rationale, design, methods, procedures and logistics for a pilot study aimed at evaluating acupuncture and moxibustion for neuropathy associated with HIV. Using STRICTA guidelines as a template, aspects of clinical research design are explored to further optimise future studies of TCM.
Adverse event reporting in acupuncture clinical trials focusing on pain.Capili, B., Anastasi, J. K., & Geiger, J. N. (2010). The Clinical journal of pain, 26, 43-8, 10.1097/AJP.0b013e3181b2c985
To review the quality of adverse event reporting for published randomized controlled trials (RCTs) focusing on acupuncture for pain reduction. With the release of the Consolidated Standards of Reporting Trials (CONSORT) in 2001, the quality of published RCTs has improved. To improve reporting on adverse events, CONSORT expanded the section on harms (adverse events) in 2004. This paper evaluates whether the updated harms guidelines have been implemented in RCTs evaluating acupuncture for pain relief.
Diagnosis and management of endometriosis: the role of the advanced practice nurse in primary care.Mao, A. J., & Anastasi, J. K. (2010). Journal of the American Academy of Nurse Practitioners, 22, 109-16, 10.1111/j.1745-7599.2009.00475.x
To discuss the etiology, clinical presentation, diagnosis, and management of endometriosis for the advanced practice nurse (APN) in primary care.
Endometriosis diagnosis and management of endometriosis: The role of the advanced practice nurse in primary careMao, A & Anastasi, J.K. (2010). Journal of the American Academy of Nurse Practitioners, 22, 109-116,
Designing and implementing an integrative therapies in primary care subspecialty programAnastasi, J. Capili, B., & Schenkmen, F. (2009). Nurse Educator, 34, 6, 271-275,
Distal Sensory Peripheral Neuropathy in HIV: A Case StudyAnastasi, J.K., Smolowitz, J., & Capili, B. (2009). Clinical Scholars Review, 2, 13-18, 10.1891/1939-2095.2.1.13
HIV peripheral neuropathy: Case report & clinical evaluationAnastasi, J., Smolowitz, J. & Capili, B. (2009). Clinical Scholars Review, 2, 13-17,
Body mass index and nutritional intake in patients with HIV and chronic diarrhea: a secondary analysis.Capili, B., & Anastasi, J. K. (2008). Journal of the American Academy of Nurse Practitioners, 20, 463-70, 10.1111/j.1745-7599.2008.00349.x
The purpose of this study was to examine the differences in nutritional intake and body mass index (BMI) in HIV patients with chronic diarrhea via secondary analysis of patients' nutritional diaries. A secondary purpose was to evaluate the quality of diets against national dietary guidelines.
Nutritional Intake Related to Lipid Health in HIV: A Secondary AnalysisCapili, B., & Anastasi, J.K. (2008). Journal of the American Academy of Nurse Practitioner, 20, 463-470,
Disorders of glucose metabolism in the context of human immunodeficiency virus infection.Larson, R., Capili, B., Eckert-Norton, M., Colagreco, J. P., & Anastasi, J. K. (2006). Journal of the American Academy of Nurse Practitioners, 18, 92-103, 10.1111/j.1745-7599.2006.00109.x
To discuss the pathophysiology and the current treatment approaches for the dysregulation of glucose metabolism in the context of human immunodeficiency virus (HIV) infection.
HIV and hyperlipidemia: current recommendations and treatment.Capili, B., & Anastasi, J. K. (2006). Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses, 15, 14-9, 35; quiz 20,
In recent years, CVD risk factors have been recognized among individuals living with HIV/AIDS (Dube et al., 2003) and have been associated with the medication regimen (HAART) used to manage the diseases. A specific class of HIV medication, protease inhibitors, has been implicated in elevating serum levels of triglyceride and cholesterol in treated individuals (Green, 2002; Penzak & Chuck, 2000). However, current treatments for hyperlipidemia in HIV are not always effective and can be dose-limited due to interactions with HAART regimens (Currier, 2002). Dietary guidelines by the NCEP have been recommended as the first-line approach to managing this condition. Well-controlled studies are needed to test the effectiveness of the NCEP diet on HIV-positive individuals. Published studies have focused primarily on dietary counseling and have lacked randomization, control groups, and adequate description of the counseling intervention. Because the mechanism associated with dyslipidemia and HAART is not fully understood, rigorously controlled dietary studies may provide the opportunity to investigate how diet metabolically affects lipid levels during HAART treatment.
Symptom Management of HIV-Related Diarrhea by Using Normal Foods: A Randomized Controlled Clinical TrialAnastasi, J.K., Capili, B., Kim, G., McMahon, D., & Heitkemper, M.M. (2006). Journal of the Association of Nurses in AIDS Care, 17, 47-57, 10.1016/j.jana.2006.01.005
Digitoxin metabolism by rat liver microsomes.Schmoldt, A., Benthe, H. F., & Haberland, G. (1975). Biochemical pharmacology, 24, 1639-41,
The beige mouse is an animal model for the human Chediak-Higashi syndrome, a disease characterized by giant lysosomes in most cell types. In mice, treatment with androgenic hormones causes a 20-50-fold elevation in at least one kidney lysosomal enzyme, beta-glucuronidase. Beige mice treated with androgen had significantly higher kidney beta-glucuronidase, beta-galactosidase, and N-acetyl-beta-D-glucosaminidase (hexosaminidase) levels than normal mice. Other androgen-inducible enzymes and enzyme markers for the cytosol, mitochondria, and peroxisomes were not increased in kidney of beige mice. No significant lysosomal enzyme elevation was observed in five other organs of beige mice with or without androgen treatment, nor in kidneys of beige females not treated with androgen. Histochemical staining for glucuronidase together with subcellular fractionation showed that the higher glucuronidase content of beige mouse kidney is caused by a striking accumulation of giant glucuronidase-containing lysosomes in tubule cells near the corticomedullary boundary. In normal mice lysosomal enzymes are coordinately released into the lumen of the kidney tubules and appreciable amounts of lysosomal enzymes are present in the urine. Levels of urinary lysosomal enzymes are much lower in beige mice than in normal mice. It appears that lysosomes may accumulate in beige mice because of defective exocytosis resulting either from decreased intracellular motility of lysosomes or from their improper fusion with the plasma membrane. A similar defect could account for characteristics of the Chediak-Higashi syndrome.
Clinical trial recruitment and retention of a vulnerable population: HIV patients with chronic diarrhea.Anastasi, J. K., Capili, B., Kim, G. H., & Chung, A. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates, 28, 463-8,
This article describes the recruitment and retention strategies implemented for a prospective, randomized, clinical trial conducted at a single study facility. The purpose of the study was to examine the effects of a nutritional intervention to reduce the episodes of diarrhea in patients with the human immunodeficiency virus/acquired immune deficiency syndrome. This article reviews the challenges faced by the research team during the conduct of the study and discusses the approaches implemented to reduce the barriers to study participation.
Developing an integrative therapies in primary care program.Anastasi, J. K., Capili, B., & Schenkman, F. Nurse educator, 34, 271-5, 10.1097/NNE.0b013e3181bc747a
The authors describe the development and incorporation of an integrative therapies subspecialty curriculum into a graduate nursing education program. Specialized education in integrative therapies prepares nursing students more thoroughly for primary care practice because many patients now use what is called complementary and alternative medicine in conjunction with standard medical care. Students learn to determine the safety, efficacy, and cultural significance of complementary and alternative medicine practices of their diverse patient population.
HIV and general cardiovascular risk.Capili, B., Anastasi, J. K., & Ogedegbe, O. The Journal of the Association of Nurses in AIDS Care : JANAC, 22, 362-75, 10.1016/j.jana.2010.12.002
The incidence of cardiovascular disease (CVD) is increasing in HIV-infected people. Risk factors such as hyperlipidemia, impaired glucose tolerance, and insulin resistance have become common. CVD in HIV may also be related to nontraditional risk factors including accumulation of visceral fat, inflammation secondary to HIV, and effects of some antiretroviral drugs. This cross-sectional study described the CVD risk factors of 123 adults living with HIV and calculated the 10-year estimate for general cardiovascular risk score. Results showed that approximately 25% of the participants were considered to be at high risk for developing CVD in the next 10 years. Increased waist circumference and longer duration of smoking habit were associated with elevated general cardiovascular risk scores. Similar to the general population, most of the identified risks could be modified through lifestyle management.
Nausea and vomiting in HIV/AIDS.Anastasi, J. K., & Capili, B. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates, 34, 15-24, 10.1097/SGA.0b013e31820b256a
HIV infection has become a chronic illness with the availability of potent antiretroviral agents. Many of the agents used to manage HIV, however, have been associated with distressing symptoms such as nausea and vomiting posing challenges to maintain adherence to therapy and quality of life. This article highlights the mechanism, evaluation, and management of HIV-associated nausea and vomiting. Supportive symptom management information is also presented.
Symptom management for irritable bowel syndrome: a pilot randomized controlled trial of acupuncture/moxibustion.Anastasi, J. K., McMahon, D. J., & Kim, G. H. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates, 32, 243-55, 10.1097/SGA.0b013e3181b2c920
The purpose of this pilot study was to assess the effect of an individualized traditional Chinese medicine (TCM) acupuncture and moxibustion (Acu/Moxa) treatment on symptom control in patients with irritable bowel syndrome (IBS) in a preliminary, randomized, sham/placebo-controlled trial. Twenty-nine men and women with IBS were randomized to either individualized Acu/Moxa (treatment group) or sham/placebo Acu/Moxa (control group). All subjects were assessed by a diagnostic acupuncturist for a TCM evaluation and individualized point prescription. Only those subjects assigned to the experimental group received the individually prescribed treatment. The diagnostic acupuncturist did not administer treatments and was blind to treatment assignments. All subjects kept a symptom diary for the duration of the study, enabling measurement of symptom frequency, severity, and improvement. The Clinical Global Impression Scale was administered preintervention to establish baseline severity and on completion of the 4-week, eight-session treatment intervention. After 4 weeks of twice-weekly Acu/Moxa treatment, average daily abdominal pain/discomfort improved whereas the control group showed minimal reduction. This between-group difference adjusted for baseline difference was statistically significant. The intestinal gas, bloating, and stool consistency composite score showed a similar pattern of improvement. The findings indicate that Acu/Moxa treatment shows promise in the area of symptom management for IBS.
Understanding diagnostic reasoning in TCM practice: tongue diagnosis.Anastasi, J. K., Currie, L. M., & Kim, G. H. Alternative therapies in health and medicine, 15, 18-28,
Traditional Chinese medicine (TCM) diagnosis is a complex multifaceted process that often yields multiple differential diagnoses and subdiagnoses.