Xiaoyue Liu
PhD RN
Assistant Professor
xl5272@nyu.edu
1 212 992 5994
Assistant Professor
433 FIRST AVENUE
NEW YORK, NY 10010
United States
Xiaoyue Liu's additional information
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Xiaoyue (Sherry) Liu, PhD, RN, is an Assistant Professor at NYU Rory Meyers College of Nursing. Her research interests center on cardiovascular risk and health-related behaviors, with a particular focus on sleep.
Prof. Liu has conducted projects exploring the underlying mechanisms linking sleep and blood pressure. She has also been actively involved in community-based studies on adults with hypertension. Currently, her research aims to leverage advanced technologies to develop personalized interventions for adults experiencing sleep disturbances.
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PhD, University of VirginiaPostdoctoral Training, Johns Hopkins University
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Cardiovascular HealthSleepTechnology
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American Academy of Sleep MedicineAmerican Heart AssociationSigma Theta Tau Nursing Honor Society
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Faculty Honors Awards
Health Equity Research Network Fellowship, American Heart Association RESTORE NetworkPCNA Annual Symposium Scholarship, Preventive Cardiovascular Nurses AssociationWining Abstract Award, Preventive Cardiovascular Nurses Association -
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Publications
Abstract 4140513: Temporal Trends in Cardiovascular Risk Factors and Cardiovascular Disease Among Subgroups of Asian Americans in the United States
AbstractLiu, X., & Liu, X. (2024). (p. A4140513).AbstractAims: Asian Americans experience disproportionate burdens of cardiovascular risk factors and cardiovascular disease (CVD). However, the trends in cardiovascular risks in adults from different Asian ethnic backgrounds remain understudied. Therefore, we examined the temporal trends in cardiovascular conditions among Chinese, Filipino, and Asian Indian adults living in the U.S. Methods: We conducted a cross-sectional analysis using the 2004-2018 National Health Interview Survey. Age-standardized prevalence rates were calculated for eight conditions, including hypertension, type 2 diabetes, alcohol use, smoking, physical inactivity, overweight/obesity, short sleep (< 7 hours), and CVD (defined as having coronary heart disease, heart attack, or stroke). Average annual percent change (AAPC) was employed to summarize and compare the trend of each outcome of interest over 15 years. Results: The sample consisted of 14,073 Asian adults, with 13% aged 65 years or older and 53% female. Of the sample, Filipino adults had the highest prevalence rates for most conditions, except for physical inactivity and overweight/obesity. Over 15 years, Chinese adults showed a 2% annual increase in short sleep (p = 0.010). Asian Indian adults exhibited uptrends in overweight/obesity (AAPC: 1.1%, p < 0.001) and alcohol use (AAPC: 2.3%, p < 0.001), but downtrends in smoking (AAPC: -4.8%, p = 0.005) and physical inactivity (AAPC: -0.8%, p < 0.001). Filipino adults demonstrated similar trends in the prevalence of alcohol use and smoking, with AAPCs at 1.6% (p = 0.001) and -3.1% (p = 0.001), respectively. No significant trends were found for other cardiovascular conditions in all three groups. Discussion: Our study assessed temporal trends in CVD and its risk factors among the three largest Asian ethnic groups in the U.S. The findings showed that Asian Americans from different ethnic backgrounds face varying disparities in cardiovascular health. Public health strategies should be customized to effectively address specific cardiovascular risks for each Asian subgroup.Abstract 4140555: Sleep Quality Mediates the Relationship Between Sleep Hygiene Practices and Psychological Stress Among Adults With Multiple Cardiovascular Risk Factors
AbstractLiu, X., Liu, X., Li, J., Hu, J., Fletcher, J., Commodore-Mensah, Y., & Cheryl, H. D. (2024). (p. A4140555).AbstractBackground: Psychological stress and poor sleep quality are interrelated and disproportionately affect adults who have multiple risk factors of cardiovascular disease (CVD). Sleep hygiene practices, such as maintaining an optimal household environment and engaging in healthy bedtime behaviors, are essential to sleep health. These practices may also impact psychological stress; however, their relationships remain under-studied. This study aimed to examine the associations among sleep hygiene practices, sleep quality, and psychological stress in adults with multiple CVD risk factors. Methods: Adults diagnosed with hypertension and type 2 diabetes completed an online survey (N = 300). Psychological stress and sleep quality were assessed using the Perceived Stress Scale 4 and the Pittsburgh Sleep Quality Index, respectively. A sleep hygiene instrument was used to examine 8 individual factors focusing on negative household environment (safety, physical comfort, temperature, and light) and poor in-bed behaviors (watching TV, playing video games, using screens, and eating). Multiple regression was employed to examine the association of each sleep hygiene factor with sleep quality and psychological stress. Subsequently, mediation analyses were conducted to examine the mediating role of sleep in the association between the composite sleep hygiene score and psychological stress. Results: Of the sample, 78% reported poor sleep quality and 44% reported high psychological stress. Individual sleep hygiene factors (e.g., unsafe household and eating at bedtime), as well as the composite sleep hygiene score, were significantly associated with poorer sleep quality and higher psychological stress. Sleep quality partially mediated the association between the composite sleep hygiene score and psychological stress (Indirect effect: 0.183; 95% bootstrap confidence interval: 0.057-0.339). Conclusions: The findings showed strong links between sleep hygiene practices, sleep quality, and psychological stress. Although causality cannot be inferred, current evidence suggests that promoting sleep hygiene education and implementing strategies to enhance sleep quality may alleviate psychological burdens in adults with multiple CVD risk factors.Blood Pressure Measurements Obtained by Community-Dwelling Adults Are Similar to Nurse-Obtained Measurements : The SMART-BP Validate Study
AbstractLiu, X., Slone, S. E., Chen, Y., Yeboah-Kordieh, Y., Alharthi, A., Amihere, J., Moyo-Songonuga, S., Lane, T., Ostchega, Y., Brady, T. M., Himmelfarb, C. R., & Commodore-Mensah, Y. (2024). In American Journal of Hypertension (Vols. 37, Issues 5, pp. 334-341). 10.1093/ajh/hpae001AbstractBACKGROUND: Self-measured blood pressure (SMBP) is an effective strategy for managing and controlling hypertension. However, uncertainty regarding patients' ability to accurately measure their blood pressure (BP) contributes to treatment inertia. Therefore, we compared BP measurements with the Omron HEM-9210T device obtained by nurses and community-dwelling adults after training. METHODS: This cross-sectional study was conducted in a simulated home environment at an academic institution. After a 5-min rest, a trained nurse measured a participant's BP twice at a 1-min interval. The participants then ambulated at their usual pace for 2 min. Next, they were asked to rest for 5 min, during which each individual watched a 3-min video on SMBP. Following the rest, the participants obtained two readings at a 1-min interval. RESULTS: We recruited 102 community-dwelling adults with a mean age of 54 (±14) years; 59% female, 88% Black race, and 63% with a hypertension diagnosis. Half (n=51) had a home BP monitor. Overall, there were no significant differences between nurse-and participant-obtained systolic BP (mean difference [MD]:-1.1; standard deviation [SD]: 8.0; P=0.178) or diastolic BP (MD:-0.9; SD: 5.5; P=0.111). Participants who used an extra-large cuff had higher self-measured diastolic BP (MD:-2.9; SD: 4.5; P=0.010). All participants demonstrated satisfactory SMBP skills after the training. CONCLUSIONS: Community-dwelling adults can accurately measure BP after a 3-min video training. Integrating SMBP training into patient encounters may result in reliable home BP measurements, improving hypertension management and clinical decision making.Cardiovascular Implications of Sleep Disorders Beyond Sleep Apnea
AbstractLiu, X., Park, J.- A., Yoon, J.-E. E., Liu, X., Chang, Y., Maiolino, G., Pengo, M. F., Lin, G.-M. M., & Kwon, Y. (2024). In Current sleep medicine reports (Vols. 10, Issues 3, pp. 320-328).AbstractSleep is crucial for human health and life. There is still limited attention to the association between sleep disorders beyond sleep apnea and cardiovascular (CV) health. We investigated the current evidence between non-respiratory sleep disorders and CV health.Design and rationale of the cardiometabolic health program linked with community health workers and mobile health telemonitoring to reduce health disparities (LINKED-HEARTS) program
AbstractCommodore-Mensah, Y., Chen, Y., Ogungbe, O., Liu, X., Metlock, F. E., Carson, K. A., Echouffo-Tcheugui, J. B., Ibe, C., Crews, D., Cooper, L. A., & Himmelfarb, C. D. (2024). In American Heart Journal (Vols. 275, pp. 9-20). 10.1016/j.ahj.2024.05.008AbstractBackground: Hypertension and diabetes are major risk factors for cardiovascular diseases, stroke, and chronic kidney disease (CKD). Disparities in hypertension control persist among Black and Hispanic adults and persons living in poverty in the United States. The “LINKED-HEARTS Program” (a Cardiometabolic Health Program LINKED with Community Health WorkErs and Mobile HeAlth TelemonitoRing To reduce Health DisparitieS”), is a multi-level intervention that includes home blood pressure (BP) monitoring (HBPM), blood glucose telemonitoring, and team-based care. This study aims to examine the effect of the LINKED-HEARTS Program intervention in improving BP control compared to enhanced usual care (EUC) and to evaluate the reach, adoption, sustainability, and cost-effectiveness of the program. Methods: Using a hybrid type I effectiveness-implementation design, 428 adults with uncontrolled hypertension (systolic BP ≥ 140 mm Hg) and diabetes or CKD will be recruited from 18 primary care practices, including community health centers, in Maryland. Using a cluster-randomized trial design, practices are randomly assigned to the LINKED-HEARTS intervention arm or EUC arm. Participants in the LINKED-HEARTS intervention arm receive training on HBPM, BP and glucose telemonitoring, and community health worker and pharmacist telehealth visits on lifestyle modification and medication management over 12 months. The primary outcome is the proportion of participants with controlled BP (Disparities in sleep care and cardiovascular outcomes: defining the problem and implementing solutions
AbstractLiu, X., Healy, W. J., Johnson, D. A., Liu, X., Jean-Louis, G., & Kwon, Y. (2024). In Journal of clinical sleep medicine.Abstract~Heterogeneities in sleep duration and quality among U.S. immigrants from different racial and ethnic backgrounds
AbstractLiu, X., Li, J., Cho, Y., & Wu, B. (2024). In Sleep Health. 10.1016/j.sleh.2024.03.006AbstractObjectives: Sleep plays an essential role in well-being. Although U.S. immigrants are considerably growing, few studies have examined sleep in this diverse population, particularly those from Asian backgrounds. It is also unclear how sleep differs by the length of residence across immigrant groups. In this study, we examined the relationships among race/ethnicity, length of residence, and sleep using a nationally representative cohort of U.S. immigrants. Methods: We analyzed data from the 2013-2018 National Health Interview Survey. The sample (N = 27,761; 14% ≥65 years old) included foreign-born adults from the following racial/ethnic backgrounds: non-Hispanic White, non-Hispanic Black, Asian (Chinese, Filipino, Asian Indian), and Hispanic/Latino. Length of residence was categorized asObstructive sleep apnea and hypertension; critical overview
AbstractKwon, Y., Tzeng, W. S., Seo, J., Logan, J. G., Tadic, M., Lin, G. M., Martinez-Garcia, M. A., Pengo, M., Liu, X., Cho, Y., Drager, L. F., Healy, W., & Hong, G. R. (2024). In Clinical Hypertension (Vols. 30, Issue 1). 10.1186/s40885-024-00276-7AbstractObstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA’s effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.Physical Activity Engagement among Black Immigrants and African American Adults in the 2010 to 2018 NHIS Study
AbstractAjibewa, T. A., Turkson Ocran, R. A., Carnethon, M. R., Metlock, F. E., Liu, X., & Commodore-Mensah, Y. (2024). In Ethnicity and Disease (Vols. 34, Issues 3, pp. 165-172). 10.18865/EthnDis-2023-45AbstractBackground: High rates of physical inactivity persist in the United States, with higher rates among non-Hispanic Black adults than among their White peers. However, a comparison of physical activity engagement across nativity among Black adults in the United States has yet to be fully documented. The purpose of this cross-sectional study was to examine physical activity engagement rates among African immigrant and Afro-Caribbean immigrant adults compared with native-born African American adults using data from the 2010 to 2018 National Health Interview Survey. Methods: Using data from the 2010 to 2018 National Health Interview Survey, we used generalized linear models to compare levels of physical activity (meeting the moderate-to-vigorous physical activity [MVPA] recommendations) by ethnic subgroups of Black adults, sequentially adjusting for sociodemographic and health-related risk factors. Results: Data from 38,037 adults (58.8% female, 21% college/graduate degree, and 41.4% with obesity) were included. Only 41.9% of all participants met the MVPA recommendations. In the fully adjusted models across the 9 years, higher levels of MVPA were seen among African Americans (42%) than among African immigrants (38%) and Afro-Caribbean immigrants (41%). Compared with African Americans, African immigrants were less likely to engage in physical activity that met the MVPA guidelines (prevalence ratio: 0.90; 95% confidence interval: 0.85, 0.96), whereas there were no differences in meeting the guidelines between Afro-Caribbean immigrants (prevalence ratio: 0.96; 95% confidence interval:0.90, 1.02) and African Americans. Conclusion: Culturally tailored interventions addressing socioenvironmental barriers and facilitators of physical activity may have important impacts on physical activity promotion and long-term disease burden among Black adults across nativity.Racial Disparity in Obstructive Sleep Apnea Care and its Impact on Cardiovascular Health
AbstractAgarwal, S., Monsod, P., Cho, Y. S., MacRae, S., Swierz, J. S., Healy, W. J., Kwon, Y., Liu, X., & Cho, Y. (2024). In Current Sleep Medicine Reports (Vols. 10, Issues 4, pp. 414-418). 10.1007/s40675-024-00308-6AbstractPurpose of Review: Racial disparities in sleep health as well as the diagnosis and treatment of sleep disorders have emerged as a key driver of cardiovascular outcomes. Obstructive sleep apnea (OSA), is characterized by repeated airway obstructions during sleep and is associated with an increased risk of cardiovascular disease. While racial and ethnic minorities have disproportionately high OSA prevalence rates, diagnosis rates remain low. One explanation behind this phenomenon are structural environmental and lifestyle barriers that prevent access to OSA care. Additionally, there remains significantly limited understanding of OSA and its causes and symptoms within communities. Recent Findings: In general, minorities have poorer sleep health due to systemic and environmental racism, which also causes an increased in conditions such as obesity that increases OSA risk. Disparities also persist within various types of OSA treatment. The most common form of treatment, continuous positive airway pressure (CPAP) has lower adherence among African Americans, as well as those living in areas with low socioeconomic status (SES), primarily minorities. There have been a small number of studies that have shown some initial success of educational campaigns about OSA within minority communities in increasing screenings and diagnoses. Peer based education has been an effective technique, and there is a need for such programs to be expanded. Summary: Disparities persist, with minority groups having worse sleep health and lower rates of adherence to OSA treatment. Some grassroots, peer-led educational campaigns show promise in increasing adherence. In light of these disparities, there remains a need for the field of sleep medicine to continue addressing the systemic barriers that hinder the timely evaluation and treatment in racial minorities. -