Bei Wu

Faculty

Bei Wu headshot

Bei Wu

FAAN FGSA PhD

Dean's Professor in Global Health
Vice Dean, Research
Affiliated Professor, Ashman Department of Periodontology & Implant Dentistry
Co-director, NYU Aging Incubator

1 212 992 5951

433 First Ave
New York, NY 10010
United States

Accepting PhD students

Dr. Wu is Dean’s Professor in Global Health and Vice Dean for Research at the NYU Rory Meyers College of Nursing. She is an inaugural Co-Director of the NYU Aging Incubator. Prior to joining NYU, she was the Pauline Gratz Professor of Nursing at Duke University School of Nursing. Prof. Wu is an internationally-known leader in gerontology.

As a principal investigator, Prof. Wu has led numerous projects supported by federal agencies and private foundations, including the NIH and CDC. She is currently leading several NIH-funded projects including a clinical trial to improve oral health for persons

with cognitive impairment, and a large secondary data analysis to examine how the co-occurrence of diabetes and poor oral health may lead to the development of dementia and cognitive decline. She co-leads the newly funded Rutgers-NYU Center for Asian Health Promotion and Equity. Through this center, she also leads a 5-year intervention study that focuses on supporting Chinese and Korean dementia caregivers who are at increased risk for high blood pressure and diabetes due to the physical and emotional demands of caregiving. She is a director of the Research and Education Core for the NIA-funded Asian Resource Center for Minority Aging Research (RCMAR).

As a scholar, Prof. Wu is an internationally known leader in gerontology. Her scholarship has been distinguished by interdisciplinary collaborations with researchers in various disciplines, including nursing and dentistry, in the US and abroad. Her research areas cover a wide range of topics related to aging and global health, including oral health, long-term care, dementia, and caregiving. She is one of the first in the nation to study the linkages between oral health and cognitive decline in older adults. Her research has also addressed knowledge gaps in the linkages between oral health and diabetes.

Prof. Wu has devoted much of her time to training the next generation of aging and nursing scientists from dozens of academic institutions in the U.S. and abroad. She has mentored hundreds of faculty members, visiting scholars, and students from various disciplines, including nursing, gerontology, dentistry, medicine, social work, demography, public health, sociology, public policy, geography, and economics. She is successful in mentoring several dozens of early-stage faculty members in receiving competitive funding from NIH, Robert Wood Johnson Scholars, the Alzheimer’s Society (UK), National Science Foundation of China, China Medical Board, National Medical Research Council (Singapore), and many others. 

Prof. Wu is a productive researcher. She has published more than 600 peer-reviewed papers, books, reports, and conference abstracts. Her extensive publications cover a wide range of topics related to aging and global health. She has delivered presentations at hundreds of conferences as an invited speaker. Her work has been widely recognized in the field. Research findings from her team have been featured by the National Institute on Aging, and in numerous media outlets, including the New York Times, CNN, BBC, U.S. News and World Report, MarketWatch, CBS News, Reuters, AARP Bulletin, China Daily, Daily Mail, South China Morning Post, and Financial Review.

Her achievement has been recognized by many international and national organizations and she is a fellow of the Gerontological Society of America, the Association for Gerontology in Higher Education, and the New York Academy of Medicine. She is an honorary member of the Honor Society of Nursing, Sigma Theta Tau International, and is the former president of the Geriatric Oral Research Group of the International Association for Dental Research. She has served on a number of NIH review panels and is a frequent reviewer for multiple international funding agencies. She was honored as the 2017 IADR Distinguished Scientist in Geriatric Oral Research. She is the recipient of the 2022 Wei Hu Inspiration Award from the China Health Policy and Management Society. 

PhD - Gerontology Center, University of Massachusetts, Boston
MS - Gerontology Center, University of Massachusetts, Boston
BS - Shanghai University

Gerontology
Global

Honorary Member, Sigma Theta Tau International - Honor Society of Nursing

Distinguished Scientist Award for Geriatric Oral Research, International Association for Dental Research (2017)
Pauline Gratz Professorship, Duke University School of Nursing (2014)
J. Morita Junior Investigator Award in Geriatric Oral Health, International Association for Dental Research (2007)
Fellow, Gerontological Society of America
Fellow, New York Academy of Medicine
Fellow, Association for Gerontology in Higher Education

Poststroke activity engagement in community dwellers: Association with illness perceptions and perceived environment

Shi, Y., Howe, T. H., Halpin, P. F., & Wu, B. (2023). Clinical Rehabilitation, 37(1), 132-142. 10.1177/02692155221111926
Abstract
Abstract
Objectives: To investigate whether individuals’ poststroke activity engagement is associated with their perceptions of stroke, as well as their perceptions of physical and social environment. Design: Cross-sectional study. Setting: Participants were recruited from eight rehabilitation settings in Beijing, China. Participants: A total of 202 dyads of community dwellers with stroke and their primary caregivers. Main Measures: Activity engagement measured by the Assessment of Life Habits; stroke individuals’ and caregivers’ illness perceptions measured by the Stroke-Specific Illness Perceptions Questionnaire – Revised; and stroke individuals’ perceived social and physical environment measured by the Social Support Survey and abbreviated Neighborhood Environment Walkability Scale. Results: A total of 202 dyads of individuals with stroke and their caregivers participated in the study with mean ages of 61.3 (8.3) and 52.6 (11.6), respectively. On average, stroke individuals scored 7.61 (1.42) on the daily activities subscale, indicating that they completed personal level activities without assistance but with some difficulty. They scored 6.21 (2.21) on the social roles subscale, suggesting that individuals completed societal level activities with assistive devices and with some difficulty. Illness perceptions correlated significantly with personal level activity engagement (change in R-squared = 0.029; p = 0.049), and perceived accessibility and heterogeneity correlated significantly with societal level activity engagement (change in R-squared = 0.025; p = 0.011). Conclusions: Poststroke activity engagement is associated not only with stroke individuals’ performance skills but also with their perceptions of stroke, and how they perceive their physical environment. The findings may assist clinicians’ decision making when developing comprehensive, targeted interventions for improving activity engagement and maximizing recovery after stroke.

Prevalence and determinants of food insecurity during the 2022 COVID-19 related lockdown in Shanghai

Liu, Y., Li, G., Qi, X., Wu, B., Latkin, C. A., Tang, W., & Hall, B. J. (2023). Global Public Health, 18(1). 10.1080/17441692.2023.2246066
Abstract
Abstract
The SARS-CoV-2 coronavirus pandemic has led to increased food insecurity levels. This cross-sectional study examines the prevalence and determinants of food insecurity during the two-month (1 April to 1 June 2022) city-wide lockdown in Shanghai. The data was collected via an online questionnaire from 3230 adult Shanghai residents during the lockdown. Food insecurity was measured using an adapted version of the Household Food Insecurity Access Scale. Nearly 70% of participants reported being exposed to food insecurity. Using multivariable logistic regressions, we examined the associations between key correlates (i.e. age, income, lockdown-related income loss, migration, employment status, social capital, preparedness, and received social support) and overall food insecurity while adjusting for ethnicity, gender, education, household size, and marital status. Results showed that compared to local Shanghai residents, migrants (i.e, permanent migrants with Hukou (OR = 2.16), permanent migrants without Hukou (OR = 2.06), temporary migrants (OR = 2.74)), and participants with less than or greather than 50% lockdown-related income loss (OR = 2.60, OR = 3.09), were associated with higher odds of overall food insecurity. Participants with greater preparedness (OR = 0.66), greater bonding social capital (OR = 0.93), and greater bridging social capital (OR = 0.94), had lower odds of overall food insecurity. Targeted interventions are needed to enhance food resilience and health equity among vulnerable populations.

Prevalence and Incidence of Mild Cognitive Impairment in Adults with Diabetes in the United States

Zheng, Y., Ma, Q., Qi, X., Zhu, Z., & Wu, B. (2023). Diabetes Research and Clinical Practice, 205, 110976. 10.1016/j.diabres.2023.110976
Abstract
Abstract
BACKGROUND: Limited evidence exists about the prevalence and incidence of mild cognitive impairment (MCI) in individuals with diabetes in the U.S. We aimed to address such knowledge gaps using a nationally representative study dataset.METHOD: We conducted a secondary analysis from the Health and Retirement Study (HRS) (1996-2018). The sample for examining the prevalence of MCI was14,988, with 4,192 (28.0%) having diabetes, while the sample for the incidence was 21,824, with 1,534 (28.0%) having diabetes.RESULTS: Participants with diabetes had a higher prevalence of MCI than those without diabetes (19.9% vs. 14.8%; odds ratio [95% confidence interval] (OR[95%CI]): 1.468 [1.337, 1.611], p<.001). The incidence of MCI in participants with/without newly diagnosed diabetes was 42.9% vs. 31.6% after a mean 10-year follow-up, with the incidence rate ratio (IRR) [95%CI] (1.314 [1.213, 1.424], p<.001). Newly diagnosed diabetes was associated with elevated risks of MCI compared with non-diabetes, with the uncontrolled hazard ratio (HR) [95%CI] (1.498 [1.405, 1.597], p<.001).CONCLUSIONS: Using a nationally representative study data in the U.S., participants with diabetes had a higher prevalence and incidence of MCI than those without diabetes. Findings show the importance of developing interventions tailored to the needs of individuals with diabetes and cognitive impairment.

The promise and peril of ChatGPT in geriatric nursing education: What We know and do not know

Qi, X., Zhu, Z., & Wu, B. (2023). Aging and Health Research, 3(2). 10.1016/j.ahr.2023.100136

Quality of care in home health agencies with and without accreditation: a cohort study

Ma, C., Dutton, H. J., & Wu, B. (2023). Home Health Care Services Quarterly, 42(1), 1-13. 10.1080/01621424.2022.2123756
Abstract
Abstract
While home health agencies (HHAs) can seek accreditation to recognize their quality of service, it is unknown whether agencies with accreditation perform better in providing care than those without accreditation. Using 5-year data from national data sources, the aims of this study were: 1) to depict characteristics of HHAs with and without accreditation; and 2) to examine the relationship between accreditation status and HHA performance on quality-of-care metrics. This study analyzed 7,697 agencies in the US and found that 1) agencies that were for-profit, urban, not-hospital-affiliated, single-branch, Medicare enrolled only, and without hospice program were more likely to have accreditation; and 2) overall, accredited agencies performed better on the three commonly used quality indicators, timely initiation of care, hospitalization, and emergency department visit, though not all the observed differences were substantial in absolute value. Our results provide unique empirical information to agencies considering seeking accreditation.

Quality of death among older adults in China: The role of medical expenditure and timely medical treatment

Gong, X., Pei, Y., Zhang, M., & Wu, B. (2023). Journal of Aging and Social Policy, 35(5), 667-682. 10.1080/08959420.2022.2079907
Abstract
Abstract
Medical expenses in the last year of life consume a large portion of healthcare expenditures, yet little is known about the relationship between medical expenditures in the last year of life and quality of death. Few empirical studies have investigated the association between timely medical treatment before dying and quality of death. This study aimed to examine the associations between medical expenditures in the last year of life, timely medical treatment before dying, and quality of death. Data derived from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), the largest national representative study of the oldest-old in China. Results from multinomial logistic regression suggested that higher medical expenses in the last year of life and lack of timely medical treatment before dying are associated with lower quality of death. These findings highlight an urgent need for strengthening education on death and dying, developing hospice and palliative care services, and improving pain management at the end of life in China.

Rehabilitation effect of intelligent rehabilitation training system on hemiplegic limb spasms after stroke

Hao, M., Fang, Q., Wu, B., Liu, L., Tang, H., Tian, F., Chen, L., Kong, D., & Li, J. (2023). Open Life Sciences, 18(1). 10.1515/biol-2022-0724
Abstract
Abstract
This article aimed to explore the rehabilitation efficacy of intelligent rehabilitation training systems in hemiplegic limb spasms after stroke and provided more theoretical basis for the application of intelligent rehabilitation systems in the rehabilitation of hemiplegic limb spasms after stroke. To explore the rehabilitation efficacy of intelligent rehabilitation training system (RTS for short here) in post-stroke hemiplegic limb spasms, this study selected 99 patients with post-stroke hemiplegic limb spasms admitted to a local tertiary hospital from March 2021 to March 2023 as the research subjects. This article used blind selection to randomly divide them into three groups: control group 1, control group 2, and study group, with 33 patients in each group. Control group 1 used a conventional RTS, group 2 used the brain-computer interface RTS from reference 9, and research group used the intelligent RTS from this article. This article compared the degree of spasticity, balance ability score, motor function score, and daily living activity score of three groups of patients after 10 weeks of treatment. After 10 weeks of treatment, the number of patients in the study group with no spasms at level 0 (24) was significantly higher than the number of patients in group 1 (7) and group 2 (10), with a statistically significant difference (P < 0.05); In the comparison of Barthel index scores, after ten weeks of treatment, the total number of people in the study group with scores starting at 71-80 and 81-100 was 23. The total number of people in the score range of 71-80 and 81-100 in group 1 was 5, while in group 2, the total number of people in this score range was 8. The study group scored considerably higher than the control group and the difference was found to be statistically relevant (P < 0.05). In the Berg balance assessment scale and motor function assessment scale, after 10 weeks of treatment, the scores of the study group patients on both scales were significantly higher than those of group 1 and group 2 (P < 0.05). The intelligent RTS is beneficial for promoting the improvement of spasticity in stroke patients with hemiplegic limb spasms, as well as improving their balance ability, motor ability, and daily life activities. Its rehabilitation effect is good.

Residential Segregation, Perceived Neighborhood Environment, and All-Cause Mortality among Community-Dwelling Older Chinese Americans

Jiang, Y., Zhu, Y., Tang, F., Chung, T., & Wu, B. (2023). Journals of Gerontology - Series B Psychological Sciences and Social Sciences, 78(12), 2071-2079. 10.1093/geronb/gbad132
Abstract
Abstract
Objectives: Residential segregation profoundly affects mental and physical health. However, impacts of residential segregation and other neighborhood characteristics on health among older Asian Americans are not fully understood. This study aimed to close this gap by examining effects of residential segregation, perceived neighborhood cohesion, and neighborhood disorder on all-cause mortality among older Chinese immigrants, as well as testing whether the association between residential segregation and mortality would be mediated by perceived neighborhood cohesion and neighborhood disorder. Methods: Data were drawn from a subsample of 3,094 older Chinese Americans aged 60 and older (mean age = 72.8 years) from the Population Study of Chinese Elderly in Chicago. Residential segregation was derived using 2010-2014 American Community Survey data. Participants completed surveys on perceived neighborhood cohesion and neighborhood disorder between 2011 and 2013. All-cause mortality was tracked until December 2021. Results: Residential segregation was associated with elevated all-cause mortality risk; this association, however, was no longer statistically significant after controlling for sociodemographic, behavioral, and health covariates. Perceived neighborhood cohesion, but not neighborhood disorder, was significantly associated with decreased mortality risks. There were no indirect effects of residential segregation on all-cause mortality through perceived neighborhood cohesion or neighborhood disorder. These effects were consistent across male and female participants. Discussion: These results suggest the importance of neighborhood social environment, specifically perceptions of neighborhood cohesion, in influencing mortality risk among older Chinese immigrants. The findings also indicate the need to conduct further research to examine the health impact of residential segregation among this population.

Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness

Ge, S., Pan, W., Wu, B., Plassman, B. L., Dong, X. Q., & McConnell, E. S. (2023). Frontiers in Neuroscience, 16. 10.3389/fnins.2022.1092297
Abstract
Abstract
Background: Multiple studies have reported that hearing and vision impairment are linked to cognitive decline. Yet little is known about factors that may influence the association between sensory impairment and cognitive decline. This study examined if loneliness mediates or moderates the impact of sensory impairment on cognitive decline as individuals age. Methods: This was a longitudinal study using data from the Health and Retirement Study (HRS) and The Aging, Demographics, and Memory Study (ADAMS) (N = 243). We used one timepoint of hearing and vision (ADAMS 2006–2008), one timepoint of loneliness (HRS 2006–2008), and five waves of cognition (HRS 2006–2014). Hearing impairment was defined by an inability to hear pure-tone stimuli of 25 dB at frequencies between 0.5 and 4.0 kHz in either ear. Visual impairment was defined as having corrected binocular vision worse than 20/40. Longitudinal parallel-process (LPP) analysis was conducted at a significance level of α = 0.05 (one-tailed). Results: Loneliness moderated but did not mediate the association between visual impairment and the rate of cognitive decline (standardized β =−0.108, p < 0.05). No moderation or mediation effect of loneliness was found for the association between hearing impairment and cognitive decline. Both vision and hearing impairment were significantly associated with increased severity of loneliness. Conclusion: Visual impairment combined with an elevated level of loneliness may produce a more synergistic, deleterious impact on older adults’ cognitive function than visual impairment alone. This study highlights the importance of promoting a healthy social and psychological status for older adults with sensory impairment.

Sex differences in the mediating role of chronic inflammation on the association between social isolation and cognitive functioning among older adults in the United States

Qi, X., Ng, T. K. S., & Wu, B. (2023). Psychoneuroendocrinology, 149. 10.1016/j.psyneuen.2023.106023
Abstract
Abstract
Background: Previous research has reported the association between social isolation and cognitive impairment. However, biological mechanisms underlying this association are understudied. It is also unclear whether there are sex differences in these biological mechanisms. Objectives: To examine whether chronic inflammation biomarkers are potential mediators of the association between social isolation and cognitive functioning among older men and women. Methods: Data were the National Health and Nutrition Examination Survey 1999–2002. A total of 2535 older adults aged 60 and older were included. Chronic inflammation was measured by C-reactive protein (CRP), plasma fibrinogen, and serum albumin. Cognitive functioning was assessed by the Digit Symbol Substitution Test (DSST). Social isolation was defined using a 4-point composite index of items pertaining to the strength of social network and support. Linear regression models and formal mediation analysis were applied. Results: Social isolation was associated with lower DSST scores [β (SE) = −2.445 (1.180), p < 0.01 for men; β (SE) = −5.478 (1.167), p < 0.001 for women]. For older men, social isolation was associated with higher levels of CRP (β [SE] = 0.226 (0.110), p < 0.05) and fibrinogen (β [SE] = 0.058 (0.026), p < 0.05). In mediation analyses, among older men, CRP mediated 6.1% and fibrinogen mediated 12.0% of the association of social isolation with DSST. Conclusion: Social isolation was associated with poorer cognitive functioning partially via heightened inflammatory responses in older men. Defining these associations’ mechanisms in sex-specific contexts could inform preventive and therapeutic strategies for cognitive impairment in older adults.