Nicole Beaulieu Perez
PhD PMHNP RN
nbp273@nyu.edu 1 212 992 9426433 FIRST AVENUE
NEW YORK, NY 10010
United States
Nicole Beaulieu Perez's additional information
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Nicole Beaulieu Perez is an assistant professor of nursing. She is a nurse scientist and board-certified psychiatric mental health nurse practitioner dedicated to improving whole health, advancing health equity, and reducing mental health stigma. Her research examines biological and social underpinnings of depression across diverse populations of women with chronic conditions (diabetes, cardiovascular disease, HIV). Perez’s interdisciplinary scholarship integrates precision health (e.g. epigenetic, gut microbiome) and advanced statistical approaches to disentangle depression with the goal of developing strategies to improve clinical identification and develop strategies for populations most at risk.
Currently, Perez is principal investigator of a P20 center pilot award funded by the National Institute of Nursing Research in which she is investigating inflammatory and epigenetic biomarkers of depressive symptom phenotypes in type 2 diabetes among women with and without HIV. She has published widely on the topics of mental health, the intersection of depression with chronic illnesses, and disparities in mental healthcare. She has presented her work at national and international nursing and translational science conferences, and her research has been featured in HuffPost, Fortune, and The Root.
For more than a decade, Perez has been a practicing psychiatric nurse and nurse practitioner across inpatient, rural clinic, and urban shelter settings, experiences that fuel her commitment to improving mental health and reducing disparities through her research and teaching. Prior to poining the NYU faculty, she completed postdoctoral training at NYU Meyers Center for Precision Health in Diverse Populations and a TL1-funded predoctoral fellowship through NYU Grossman School of Medicine Clinical and Translational Science Institute. She has also served as adjunct clinical faculty at Meyers, teaching in the graduate research courses and undergraduate psychiatric mental health courses. Perez earned her PhD from NYU Meyers College of Nursing and her BSN and MSN from the University of Florida.
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PhD, Nursing Research and Theory Development - New York UniversityMSN, Psychiatric Mental Health Advanced Practice Nursing- University of FloridaBSN, Professional Nursing- University of Florida
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Mental healthChronic diseaseUnderserved populations
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American Academy of NursingNew York Academy of SciencesInternational Society of Nurses in GeneticsEastern Nursing Research SocietyInternational Society of Psychiatric NursesAmerican Psychiatric Nurses AssociationSigma Theta Tau International Honor Society of Nursing
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Faculty Honors Awards
Distinguished PhD Student Award, NYU Meyers (2021)Ellen D. Baer Scholarship, NYU Meyers (2020) (2020)Alumnae Association Scholarship, Mount Sinai Hospital School of Nursing (2020)Board of Directors Scholarship, American Psychiatric Nurses Association (2020)Pauline Greenridge Scholarship, NYU Meyers (2019)Fred Schmidt Scholarship, NYU Meyers (2019)Psychiatric Mental Health Nursing Scholar, Barbara Jonas Foundation (2017)Rose Rivers’ Leadership Fellow, University of Florida Health (2012)Excellence in Research Award, University of Florida (2011)Sigma Theta Tau International Honor Society of Nursing Inductee, University of Florida (2010) -
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Publications
Heterogeneous depressive symptom trajectories among women with type 2 diabetes: findings from the Women’s Interagency HIV Study
Failed retrieving data.Epigenome-Wide Association Study of Depressive Symptoms in Black Women in the InterGEN Study
Failed retrieving data.Social determinants of inflammatory markers linking depression and type 2 diabetes among women: A scoping review
AbstractPerez, N., He, N., Wright, F., Condon, E., Weiser, S., & Aouizerat, B. (2024). Journal of Psychosomatic Research, 184. 10.1016/j.jpsychores.2024.111831AbstractObjective: Inflammation is implicated in the pathophysiology of depression and type 2 diabetes (T2D) and is linked to social determinants of health (SDoH) associated with socioeconomic disadvantage. The objective of this review is to identify and map the range of SDoHs associated with inflammation in depression, T2D, or their co-occurrence among women. Methods: PubMed, CINAHL, PsychINFO, and Web of Science were searched March–July 2023 to identify studies where 1) an SDoH was a predictor or independent variable, 2) depression or T2D was a clinical focus, 3) inflammatory markers were collected, and 4) analysis was specific to women. We used the National Institute on Minority Health and Health Disparities research framework to guide searching SDoHs, organize findings, and identify gaps. Results: Of the 1135 studies retrieved, 46 met criteria. Within the reviewed studies, the most used inflammatory measures were C-reactive protein, interleukin-6, and tumor necrosis factor-α, and the most studied SDoHs were early life stress and socioeconomic status. Individual and interpersonal-level variables comprised the bulk of SDoHs in the included studies, while few to no studies examined built environment (n = 6) or health system level (n = 0) factors. Disadvantageous SDoHs were associated with higher levels of inflammation across the included studies. Conclusion: The scope and intersection of depression and T2D represent a syndemic that contributes to and results from socioeconomic inequities and disproportionately affects women. Simultaneous inclusion of social and inflammatory measures, particularly understudied SDoHs, is needed to clarify potent targets aimed at advancing health and equity.Study Protocol Using Cohort Data and Latent Variable Modeling to Guide Sampling Women with Type 2 Diabetes and Depressive Symptoms
Failed retrieving data.Associations Between DNA Methylation Age Acceleration, Depressive Symptoms, and Cardiometabolic Traits in African American Mothers From the InterGEN Study
Failed retrieving data.Gut Microbiota and Depressive Symptoms at the End of CRT for Rectal Cancer: A Cross-Sectional Pilot Study
AbstractGonzalez-Mercado, V. J., Lim, J., Saligan, L. N., Perez, N., Rodriguez, C., Bernabe, R., Ozorio, S., Pedro, E., Sepehri, F., & Aouizerat, B. (2021). Depression Research and Treatment, 2021. 10.1155/2021/7967552AbstractBackground. The role of alterations in gut microbiota composition (termed dysbiosis) has been implicated in the pathobiology of depressive symptoms; however, evidence remains limited. This cross-sectional pilot study is aimed at exploring whether depressive symptom scores changed during neoadjuvant chemotherapy and radiation therapy to treat rectal cancer, and if gut microbial taxa abundances and predicted functional pathways correlate with depressive symptoms at the end of chemotherapy and radiation therapy. Methods. 40 newly diagnosed rectal cancer patients (ages 28-81; 23 males) were assessed for depressive symptoms using the Hamilton Rating Scale for Depression (HAM-D) and provided stool samples for 16S rRNA sequencing. Gut microbiome data were analyzed using QIIME2, and correlations and regression analyses were performed in R. Results. Participants had significantly higher depressive symptoms at the end as compared to before CRT. The relative abundances of Gemella, Bacillales Family XI, Actinomyces, Streptococcus, Lactococcus, Weissella, and Leuconostocaceae were positively correlated (Spearman’s rho=0.42 to 0.32), while Coprobacter, Intestinibacter, Intestimonas, Lachnospiraceae, Phascolarctobacterium, Ruminiclostridium, Ruminococcaceae (UCG-005 and uncultured), Tyzzerella, and Parasutterella (Spearman’s rho=−0.43 to−0.31) were negatively correlated with HAM-D scores. Of the 14 predicted MetaCyc pathways that correlated with depressive symptom scores at the end of CRT, 11 (79%) were associated with biosynthetic pathways. Conclusions. Significant bacterial taxa and predicted functional pathways correlated with depressive symptoms at the end of chemotherapy and radiation therapy for rectal cancer which warrants further examination and replication of our findings.Inequities along the Depression Care Cascade in African American Women: An Integrative Review
Failed retrieving data.A Microbial Relationship Between Irritable Bowel Syndrome and Depressive Symptoms
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