Publications

Publications

Dental Care Utilization Among Caregivers Who Care for Older Adults

Wu, B., Luo, H., Flint, E., & Qin, L. (2015). Research on Aging, 37(4), 388-412. 10.1177/0164027514537082
Abstract
Abstract
The goal of this study was to investigate individual and contextual factors associated with dental care utilization by U.S. informal caregivers. The sample included all 2010 Behavioral Risk Factor Surveillance System respondents who completed the caregiver module and reported providing care for 1 year or more to an individual aged ≥ 50 years or older (n = 1,196). Multiple logistic regressions were used to examine associations of caregiver and care characteristics and county-level contextual characteristics (from Area Resource File data) with two outcomes: dental visits and dental cleaning during previous year. Caregivers with health insurance coverage and higher education were more likely to use dental care; those who had lost more teeth and who were spouse caregivers were less likely to do so. Community characteristics were not correlated with caregivers’ use of dental care. Our findings suggest that better access to dental care could improve dental care utilization by caregivers.

Dental care utilization among older adults with cognitive impairment in the USA

Lee, K. H., Wu, B., & Plassman, B. L. (2015). Geriatrics and Gerontology International, 15(3), 255-260. 10.1111/ggi.12264
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Aim: We examined the relationship between cognitive impairment and dental care utilization among older adults in the USA. Methods: A total of 329 older adults aged 70 years and older in West Virginia, USA, were included in the present analyses. We carried out multivariate ordinal regression analyses. Results: Individuals with dementia were less likely to visit a dentist regularly, and more time had passed since their last dental visit compared with individuals with normal cognitive function. However, the pattern of dental care utilization for those with cognitive impairment, not dementia did not differ from individuals with normal cognition. A perceived greater social network and having dental insurance were associated with increased dental care utilization. Conclusions: Less dental care utilization might contribute to the oral health problems often observed among individuals with dementia. Efforts to increase the use of dental care should include cost-effective options for dental insurance. In addition, educating formal and informal caregivers on the importance of dental care might be beneficial, as these individuals are in the best position to facilitate dental care for individuals with dementia.

Detection rates for aneuploidy by first-trimester and sequential screening

Baer, R. J., Flessel, M. C., Jelliffe-Pawlowski, L. L., Goldman, S., Hudgins, L., Hull, A. D., Norton, M. E., & Currier, R. J. (2015). Obstetrics and Gynecology, 126(4), 753-759. 10.1097/AOG.0000000000001040
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Abstract
OBJECTIVE: To estimate detection rates for aneuploidy by first-trimester and sequential screening. METHODS: The study included women with singleton pregnancies who participated in the California Prenatal Screening Program with estimated delivery dates from August 2009 to December 2012 who had first- or firstand second-trimester (sequential) screening. Detection rates were measured for target (trisomies 21 and 18) and other aneuploidies identified from the California Chromosome Defect Registry. RESULTS: Of 452,901 women screened, 17,435 (3.8%) were screen-positive for Down syndrome only; 433 (0.1%) for trisomy 18 only; 1,689 (0.4%) for both Down syndrome and trisomy 18; and 2,947 (0.7%) for neural tube defects, Smith-Lemli-Opitz syndrome, or for multiple conditions. The detection rates were Down syndrome-92.9% (95% confidence interval [CI] 91.4-94.2); trisomy 18-93.2% (95% CI 90.5-95.9); trisomy 13-80.4% (95% CI 73.9-86.9); 45,X-80.1% (95% CI 73.9-86.3), and triploidy-91.0% (95% CI 84.2-97.9). Overall, the detection rate for chromosome abnormalities was 81.6% (95% CI 80.0-83.1) at an overall false-positive rate of 4.5%. CONCLUSION: First-trimester and sequential screening are sensitive and specific for the broad range of karyotype abnormalities seen in the population.

Development and implementation of a peer mentoring program for early career gerontological faculty

Bryant, A. L., Aizer Brody, A., Perez, A., Shillam, C., Edelman, L. S., Bond, S. M., Foster, V., & Siegel, E. O. (2015). Journal of Nursing Scholarship, 47(3), 258-266. 10.1111/jnu.12135
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Purpose: The Hartford Gerontological Nursing Leaders (HGNL) formerly known as the Building Academic Geriatric Nursing Capacity Initiative (BAGNC), in conjunction with the National Hartford Centers of Gerontological Nursing Excellence (NHCGNE), developed and executed a peer mentoring program beginning in 2011 to enhance both (a) the experience of newly selected scholars and fellows to the NHCGNE and (b) the ongoing professional development of HGNL members. The purpose of this article is to describe key strategies used to develop and execute the peer mentoring program and to present formative program evaluation. Design: The program was launched in January 2011 with seven peer mentor and mentee matches. In June 2012, the peer mentoring committee solicited feedback on the development of the peer mentoring program and changes were made for the subsequent cohorts. Findings: An additional 12 matches were made in the following 2 years (2012 and 2013), for a total of 31 matches to date. We have learned several key lessons from our three cohorts regarding how to structure, implement, and carefully evaluate a peer mentoring program. Conclusions: Informal evaluation of our peer mentoring program noted several challenges for both peer mentors and mentees. Having knowledge of and addressing those challenges may increase the overall quality and effectiveness of peer mentoring programs and, in turn, benefit academic nursing by strengthening the faculty workforce. Clinical Relevance: Findings from development and implementation of a peer mentoring program for gerontological faculty could lead to new and adaptable programs in a variety of clinical and education settings.

Diabetes learning in virtual environments: Testing the efficacy of self-management training and support in virtual environments (randomized controlled trial protocol)

Vorderstrasse, A. A., Melkus, G. D., Pan, W., Lewinski, A. A., & Johnson, C. M. (2015). Nursing Research, 64(6), 485-493. 10.1097/NNR.0000000000000128
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Abstract
Background: Ongoing self-management improves outcomes for those with Type 2 diabetes (T2D); however, there are many barriers to patients receiving assistance in this from the healthcare system and peers. Findings from our pilot study showed that a virtual diabetes community on the Internet with real-time interaction among peers with T2D - and with healthcare professionals - is feasible and has the potential to influence clinical and psychosocial outcomes. Objective: The purpose of this article is to present the protocol for the Diabetes Learning in Virtual Environments (LIVE) trial. Protocol: Diabetes LIVE is a two-group, randomized controlled trial to compare effects of a virtual environment and traditional Web site on diet and physical activity. Our secondary aims will determine the effects on metabolic outcomes; effects of level of engagement and social network formation in LIVE on behavioral outcomes; potential mediating effects of changes in self-efficacy; and diabetes knowledge, diabetes-related distress, and social support on behavior change and metabolic outcomes. We will enroll 300 subjects at two sites (Duke University/Raleigh-Durham, NC and New York University/New York, NY) who have T2D and do not have serious complications or comorbidities. Those randomly assigned to the intervention group have access to the LIVE site where they can find information, synchronous classes with diabetes educators, and peer support to enhance self-management. Those in the control group have access to the same informational and educational content in a traditional asynchronous Web format. Measures of self-management, clinical outcomes, and psychosocial outcomes are assessed at baseline and 3, 6, 12, and 18 months. Discussion: Should LIVE prove effective in improved self-management of diabetes, similar interventions could be applied to other prevalent chronic diseases. Innovative programs such as LIVE have potential for improving healthcare access in an easily disseminated alternative model of care that potentially improves the reach of self-management training and support.

Diabetes: Christian Worldview, Medical Distrust and Self-Management

Newlin Lew, K., Arbauh, N., Banach, P., & Melkus, G. (2015). Journal of Religion and Health, 54(3), 1157-1172. 10.1007/s10943-015-0022-9
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Abstract
To inform the development of a combined diabetes prevention and self-management intervention in partnership with church communities, this study sampled African American church leaders and members (N = 44) to qualitatively study religious beliefs and practices, diabetes prevention and self-management behaviors, and related community actions. Prior to commencing the study, internal review board approval was obtained. Although not required, community consent was officially provided by the church pastors. Individual consent was subsequently obtained from eligible community members who expressed an interest in participating in the study. Following a participatory action research approach, the inquiry group method was used. Qualitative data were analyzed with content analysis. Findings revealed Christian worldview, medical distrust and self-management as prominent themes. Findings suggest that diabetes providers address religious orientation in the provision of care with attention to rebuilding trust with the African-American community to improve health outcomes.

Dietary variety is inversely associated with body adiposity among us adults using a novel food diversity index

Vadiveloo, M., Beth Dixon, L., Mijanovich, T., Elbel, B., & Parekh, N. (2015). Journal of Nutrition, 145(3), 555-563. 10.3945/jn.114.199067
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Abstract
Background: Consuming a variety (vs. monotony) of energy-poor, nutrient-dense foods may help individuals adhere to dietary patterns favorably associated with weight control. Objective: The objective of this study was to examine whether greater healthful food variety quantified using the US Healthy Food Diversity (HFD) index favorably influenced body adiposity. Methods: Men and nonpregnant, nonlactating women aged ≥20 y with two 24-h recalls from the cross-sectional NHANES 2003-2006 (n = 7470) were included in this study. Dietary recalls were merged with the MyPyramid Equivalent database to generate the US HFD index, which ranges from 0 to ~1, with higher scores indicative of diets with a higher number and proportion of healthful foods. Multiple indicators of adiposity including BMI, waist-to-height ratio, android-to-gynoid fat ratio, fat mass index (FMI), and percentage body fat were assessed across US HFD index quintiles. ORs and 95% CIs were computed with use of multivariable logistic regression (SAS v. 9.3). Results: The US HFD index was inversely associated with most adiposity indicators in both sexes. After multivariable adjustment, the odds of obesity, android-to-gynoid ratio >1, and high FMI were 31-55% lower (P-trend < 0.01) among women in quintile 5 vs. quintile 1 of the US HFD index. Among men, the odds of obesity, waist-to-height ratio =0.5, and android-to-gynoid ratio >1 were 40-48% lower (P-trend = 0.01) in quintile 5 vs. quintile 1 of the US HFD index. Conclusions: Higher US HFD index values were inversely associated with indicators of body adiposity in both sexes, indicating that greater healthful food variety may protect against excess adiposity. This study explicitly recognizes the potential benefits of dietary variety in obesity management and provides the foundation to support its ongoing evaluation.

Dietary Variety: An Overlooked Strategy for Obesity and Chronic Disease Control

Vadiveloo, M. K., & Parekh, N. (2015). American Journal of Preventive Medicine, 49(6), 974-979. 10.1016/j.amepre.2015.06.014

Differences in composition of symptom clusters between older and younger oncology patients

Yates, P., Miaskowski, C., Cataldo, J. K., Paul, S. M., Cooper, B. A., Alexander, K., Aouizerat, B., Dunn, L., Ritchie, C., McCarthy, A., & Skerman, H. (2015). Journal of Pain and Symptom Management, 49(6), 1025-1034. 10.1016/j.jpainsymman.2014.11.296
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Abstract
Context Older oncology patients have unique needs associated with the many physical, psychological, and social changes associated with the aging process. The mechanisms underpinning and the impact of these changes are not well understood. Identification of clusters of symptoms is one approach that has been used to elicit hypotheses about the biological and/or psychological basis for variations in symptom experiences. Objectives The purposes of this study were to identify and compare symptom clusters in younger (<60 years) and older (≥60 years) patients undergoing cancer treatment. Methods Symptom data from one Australian study and two U.S. studies were combined to conduct this analysis. A total of 593 patients receiving active treatment were dichotomized into younger (<60 years) and older (≥60 years) groups. Separate exploratory factor analyses (EFAs) were undertaken within each group to identify symptom clusters from occurrence ratings of the 32 symptoms assessed by the Memorial Symptom Assessment Scale. Results In both groups, a seven-factor solution was selected. Four partially concordant symptom clusters emerged in both groups (i.e., mood/cognitive, malaise, body image, and genitourinary). In the older patients, the three unique clusters reflected physiological changes associated with aging, whereas in the younger group the three unique clusters reflected treatment-related effects. Conclusion The symptom clusters identified in older patients typically included a larger and more diverse range of physical and psychological symptoms. Differences also may be reflective of variations in treatment approaches between age groups. Findings highlight the need for better understanding of variation in treatment and symptom burden between younger and older adults with cancer.

Does State Legislation Improve Nursing Workforce Diversity?

Travers, J., Smaldone, A., & Gross Cohn, E. (2015). Policy, Politics, and Nursing Practice, 16(3), 109-116. 10.1177/1527154415599752
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A health-care workforce representative of our nation’s diversity is a health and research priority. Although racial and ethnic minorities represent 37% of Americans, they comprise only 16% of the nursing workforce. The purpose of this study was to examine the effect of state legislation on minority recruitment to nursing. Using data from the National Conference of State Legislatures, American Association of Colleges of Nursing, and U.S. census, we compared minority enrollment in baccalaureate nursing programs of states (Texas, Virginia, Michigan, California, Florida, Connecticut, and Arkansas) before and 3 years after enacting legislation with geographically adjacent states without legislation. Data were analyzed using descriptive and chi-square statistics. Following legislation, Arkansas (13.8%–24.5%), California (3.3%–5.4%), and Michigan (8.0%–10.0%) significantly increased enrollment of Blacks, and Florida (11.8%–15.4%) and Texas (11.2%–13.9%) significantly increased enrollment of Hispanic baccalaureate nursing students. States that tied legislation to funding, encouragement, and reimbursement had larger enrollment gains and greater minority representation.

Economics of health professional education and careers : insights from a literature review

McPake, B., Squires, A., Mahat, A., & Araujo, E. M. (2015). (1–). The World Bank.

Editor's memo: Do not resuscitate

Newland, J. (2015). The Nurse Practitioner, 40(2), 12. 10.1097/01.NPR.0000459732.85027.c2

Educational gaps and solutions for early-career nurse managers' education and participation in quality improvement

Djukic, M., Kovner, C. T., Brewer, C. S., Fatehi, F., & Jun, J. (2015). Journal of Nursing Administration, 45(4), 206-211. 10.1097/NNA.0000000000000186
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Objective: The objective of this study was to examine early-career frontline nurse managers' (FLNMs') reported educational preparedness and participation in quality improvement (QI). BACKGROUND: Frontline nurse managers are vitally important for leading QI.However, it is not well known if they have adequate knowledge and skills to lead this important function. METHODS: We examined cross-sectional survey data from 42 FLNMs using descriptive statistics. RESULTS: About 30%of FLNMsreported being very prepared across 12 measured QI skills by schools or employers and 35% reported participating in a specific clinical effort to improve patient care on their unit more than once a month. More than 50% reported having good organizational support for QI, but only about 30% reported being rewarded for their contributions to QI. CONCLUSION: Our study highlights opportunities for development in QI for FLNMs and offers some solutions for nurse executives that can bridge the educational gaps.

Effect of time of birth on maternal morbidity during childbirth hospitalization in California

Lyndon, A., Lee, H. C., Gay, C., Gilbert, W. M., Gould, J. B., & Lee, K. A. (2015). American Journal of Obstetrics and Gynecology, 213(5), 705.e1-705.e11. 10.1016/j.ajog.2015.07.018
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Objective This observational study aimed to determine the relationship between time of birth and maternal morbidity during childbirth hospitalization. Study Design Composite maternal morbidities were determined using International Classification of Diseases, Ninth Revision, Clinical Modification and vital records codes, using linked hospital discharge and vital records data for 1,475,593 singleton births in California from 2005 through 2007. Time of birth, day of week, and sociodemographic, obstetric, and hospital volume risk factors were estimated using mixed effects logistic regression models. Results The odds for pelvic morbidity were lowest between 11 PM-7 AM compared to other time periods and the reference value of 7-11 AM. The odds for pelvic morbidity peaked between 11 AM-7 PM (adjusted odds ratio [AOR], 1101-1500 = 1.07; 95% confidence interval [CI], 1.06-1.09; 1501-1900 = 1.08; 95% CI, 1.06-1.10). Odds for severe morbidity were higher between 11 PM-7 AM (AOR, 2301-0300 = 1.31; 95% CI, 1.21-1.41; 0301-0700 = 1.30; 95% CI, 1.20-1.41) compared to other time periods. The adjusted odds were not statistically significant for weekend birth on pelvic morbidity (AOR, Saturday = 1.00; 95% CI, 0.98-1.02]; Sunday = 1.01; 95% CI, 0.99-1.03) or severe morbidity (AOR, Saturday = 1.09; 95% CI, 1.00-1.18; Sunday = 1.03; 95% CI, 0.94-1.13). Cesarean birth, hypertensive disorders, birthweight, and sociodemographic factors that include age, race, ethnicity, and insurance status were also significantly associated with severe morbidity. Conclusion Even after controlling for sociodemographic factors and known risks such as cesarean birth and pregnancy complications such as hypertensive disorders, birth between 11 PM-7 AM is a significant independent risk factor for severe maternal morbidity.

Elder justice: Preventing and intervening in elder mistreatment.

Boltz, M., Buckwalter, K., Cortes, T., Evans, L. K., & Fulmer, T. (2015). Nursing Outlook, 63(5), 610-613. 10.1016/j.outlook.2015.08.002

Evaluation of a high pressure liquid chromatography procedure for measuring HbA1c in gingival crevicular blood. Laboratory measurement of HbA1c in gingival crevicular blood using a high-pressure liquid chromatography procedure

Pesce, M. A., Strauss, S., Rosedale, M., Netterwald, J., & Wang, H. (2015). Laboratory Medicine, 46(4), 290-298.

Factors Associated with the Hospitalization of Patients Receiving Hospice Care

Aldridge, M., Cherlin, E., Lee, E., Brody, A., & Bradley, E. (2015). Journal of Pain and Symptom Management, 49(2), 339-339.

Factors associated with traditional Chinese medicine utilization among urban community health centers in Hubei Province of China

Cai, Y., Mao, Z., Xu, B., & Wu, B. (2015). Asia-Pacific Journal of Public Health, 27(2), NP2489-NP2497. 10.1177/1010539513491415
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This study aims to examine resources and utilization of traditional Chinese medicine (TCM) and factors influencing TCM utilization in urban community health centers (CHCs) in Hubei Province of China. A cross-sectional survey including 234 government-owned CHCs was conducted in 2009. One-way analysis of variance analysis and a Poisson regression model were used to examine distribution of TCM resources and factors influencing TCM utilization. This study found unequal distribution of TCM resources among districts. TCM outpatient visits were positively associated with higher economic development districts, lower initial capital investment of the CHCs, health services covered by health insurance, higher qualification of TCM physicians, provision of TCM health records and rehabilitation, and greater availability of herbal medicine. To achieve equal access to TCM services, policy makers should consider the socioeconomic differences and income groups, provide training for TCM physicians, build pathway to recruit senior TCM physicians, and cover more TCM therapies by health insurance.

Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: A qualitative evidence-synthesis

Jordan, J., Rose, L., Dainty, K. N., Noyes, J., Clarke, S., & Blackwood, B. (2015). Cochrane Database of Systematic Reviews, 2015(7). 10.1002/14651858.CD009851.pub2
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This is the protocol for a review and there is no abstract. The objectives are as follows: To enhance and extend the recent Cochrane effectiveness review of protocolized weaning (Blackwood 2010) by synthesizing evidence from qualitative research to identify contextual factors that impact on the use of ventilator weaning protocols for critically ill adults and children. The research questions we will address are as follows. 1. Which contextual factors may have contributed to the heterogeneity in effect sizes of the randomized controlled trials included in the Blackwood (2010) review on protocolized weaning? (enhancing the review). 2. Which contextual factors (facilitators and barriers) may have an impact on the effective use of protocols for weaning critically ill adults and children from mechanical ventilation? (extending the review).

Family caregiver's perception of Alzheimer's disease and caregiving in Chinese culture

Dai, B., Mao, Z., Wu, B., Mei, Y. J., Levkoff, S., & Wang, H. (2015). Social Work in Public Health, 30(2), 185-196. 10.1080/19371918.2014.969858
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This study examined the perception of Alzheimer's disease (AD) and caregiving among family caregivers of individuals with mild cognitive impairment (MCI) and AD in China. In-depth semistructured interviews were conducted with 46 family caregivers of individuals with cognitive impairment in 2009 in Wuhan and Beijing, China. Participants included 38 spouses, 7 adult children, and 1 sibling, aged between 41 and 85 years old. The findings showed that all family caregivers thought the Chinese terminology of AD laonian chidai, brought discrimination to individuals with cognitive impairment. Caregivers of individuals with AD experienced burden and desired an increase of formal services. Traditional beliefs of respecting elders and caring for extended family members were held among family caregivers of individuals with cognitive impairment, and there was nearly no difference found between caregivers of AD and those of MCI. It implied that traditional culture provided positive influences on caring for elders with cognitive impairment. An alternative term for MCI may contribute to further reducing the discrimination brought by the old Chinese terminology of AD laonian chidai. Development of formal services for elders with cognitive impairment may contribute to reducing caregivers' worries about future caregiving.

Fetal Heart Monitoring Principles and Practices

Lyndon, A., & Ali, L. (Eds.). (2015). (5th eds., 1–). Association of Women’s Health, Obstetric, & Neonatal Nurses/Kendall Hunt.

Find out how to respond appropriately when patients express bigotry at the bedside

Lim, F. A., & Borski, D. B. (2015). Nursing Made Incredibly Easy, 13(6), 26-31. 10.1097/01.NME.0000471849.60754.a3

Forty-year trends in tooth loss among american adults with and without diabetes mellitus: An age-period-cohort analysis

Luo, H., Pan, W., Sloan, F., Feinglos, M., & Wu, B. (2015). Preventing Chronic Disease, 12(12). 10.5888/pcd12.150309
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Introduction This study aimed to assess the trends in tooth loss among adults with and without diabetes mellitus in the United States and racial/ ethnic disparities in tooth loss patterns, and to evaluate trends in tooth loss by age, birth cohorts, and survey periods. Methods Data came from 9 waves of the National Health and Nutrition Examination Survey (NHANES) from 1971 through 2012. The trends in the estimated tooth loss in people with and without diabetes were assessed by age groups, survey periods, and birth cohorts. The analytical sample was 37,609 dentate (ie, with at least 1 permanent tooth) adults aged 25 years or older. We applied hierarchical age-period-cohort cross-classified random-effects models for the trend analysis. Results The estimated number of teeth lost among non-Hispanic blacks with diabetes increased more with age than that among non-Hispanic whites with diabetes (z = 4.05, P <.001) or Mexican Americans with diabetes (z = 4.38, P <.001). During 1971-2012, there was a significant decreasing trend in the number of teeth lost among non-Hispanic whites with diabetes (slope = -0.20, P <.001) and non-Hispanic blacks with diabetes (slope = -0.37, P <.001). However, adults with diabetes had about twice the tooth loss as did those without diabetes. Conclusion Substantial differences in tooth loss between adults with and without diabetes and across racial/ethnic groups persisted over time. Appropriate dental care and tooth retention need to be further promoted among adults with diabetes.

Friends Helping Friends: A nonrandomized control trial of a peer-based response to dating violence

Amar, A. F., Tuccinardi, N., Heislein, J., & Simpson, S. (2015). Nursing Outlook, 63(4), 496-503. 10.1016/j.outlook.2015.01.004
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Dating violence is a significant problem for older adolescents with implications for the survivor's health. Survivors disclose the violence to friends who are often ill equipped to help them manage the consequences. The purpose of this pilot study was to evaluate the effectiveness and feasibility of Friends Helping Friends, a community-level education program to teach older adolescents to recognize and intervene in dating violence. A convenience sample of 101 students aged 18 to 22 years were nonrandomly allocated to a treatment or control group and completed pre- and post-test measures. Compared with the control group, treatment group participants reported increased perceived responsibility to help, skills to act as a bystander, and intention to help and decreased rape myth acceptance. Friends Helping Friends shows promise as an effective strategy for older adolescent females in the prevention and response to dating violence.

Gender differences in predictors of quality of life at the initiation of radiation therapy

West, C., Paul, S. M., Dunn, L., Dhruva, A., Merriman, J., & Miaskowski, C. (2015). Oncology Nursing Forum, 42(5), 507-516. 10.1188/15.ONF.507-516
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Purpose/Objectives: To evaluate gender differences in quality of life (QOL), demographic, clinical, and symptom characteristics. Design: Prospective, observational. Setting: Two radiation oncology departments in northern California. Sample: 185 patients before initiation of radiation therapy (RT). Methods: At their RT simulation visit, patients completed a demographic questionnaire, a measure of QOL, and symptom-specific scales. Backward elimination regression analyses were conducted to determine the significant predictors of QOL. Main Research Variables: QOL, gender, and 20 potential predictors. Findings: In women, depressive symptoms, functional status, age, and having children at home explained 64% of the variance in QOL. In men, depressive symptoms, state anxiety, number of comorbidities, being a member of a racial or ethnic minority, and age explained 70% of the variance in QOL. Conclusions: Predictors of QOL differed by gender. Depressive symptom score was the greatest contributor to QOL in both genders. Implications for Nursing: Nurses need to assess for QOL and depression at the initiation of RT. Knowledge of the different predictors of QOL may be useful in the design of gender-specific interventions to improve QOL.