Publications
Publications
Integrating Family Caregivers into Palliative Oncology Care Using the Self- and Family Management Approach
Schulman-Green, D., & Feder, S. (2018). Seminars in Oncology Nursing, 34(3), 252-263. 10.1016/j.soncn.2018.06.006
Abstract
Objective: To describe the integration of family caregivers into palliative oncology care using the Self- and Family Management Framework. Data Sources: Peer-reviewed journal articles. Conclusion: The role of family caregivers in palliative oncology includes focusing on illness needs, activating resources, and living with cancer. Several factors may serve as facilitators of or barriers to these activities. A growing number of interventions support family caregivers’ involvement in palliative oncology care. Implications for Nursing Practice: Nurses should identify who the family caregiver is, confirm ability and willingness, discuss patients’ and family caregivers’ goals for cancer care, activate resources, and promote ongoing communication to support changing needs.
Integrating oral health curricula into nurse practitioner graduate programs: Results of a US survey
Dolce, M. C., Haber, J., Savageau, J. A., Hartnett, E., & Riedy, C. A. (2018). Journal of the American Association of Nurse Practitioners, 30(11), 638-647. 10.1097/JXX.0000000000000079
Abstract
Background and purpose: Nurse practitioners (NPs) are a significant segment of the US primary care workforce and have a pivotal role in improving access to oral health (OH) care. The purpose of this research was to assess OH curricular integration in primary care NP programs and to examine factors that influence integration and satisfaction with graduates’ level of OH competence. Methods: A cross-sectional, national survey of NP programs (N = 466) was conducted using an electronically distributed 19-item, self-administered questionnaire. Data analysis included univariate, bivariate, multivariate statistics, and logistic regression modeling. Conclusions: The large majority of pediatric, family, and adult–gerontology primary care programs are educating NP graduates about OH. Significant factors promoting integration and satisfaction with graduates’ level of competence included the presence of a faculty champion and routine teaching by a dental professional or nondental OH expert. Implications for practice: With adequate OH education, NPs are ideally positioned to integrate OH and primary care services in practice, thereby, improving access to OH care.
Inter- and intra-disciplinary collaboration and patient safety outcomes in U.S. acute care hospital units: A cross-sectional study
Ma, C., Park, S. H., & Shang, J. (2018). International Journal of Nursing Studies, 85, 1-6. 10.1016/j.ijnurstu.2018.05.001
Abstract
Background: Collaboration among healthcare providers has been considered a promising strategy for improving care quality and patient outcomes. Despite mounting evidence demonstrating the impact of collaboration on outcomes of healthcare providers, there is little empirical evidence on the relationship between collaboration and patient safety outcomes, particularly at the patient care unit level. Objectives: The purpose of this study is to identify the extent to which interdisciplinary collaboration between nurses and physicians and intradisciplinary collaboration among nurses on patient care units are associated with patient safety outcomes. Methods: This is a cross-sectional study using nurse survey data and patient safety indicators data from U.S. acute care hospital units. Collaboration at the unit level was measured by two 6-item scales: nurse-nurse interaction scale and nurse-physician interaction scale. Patient outcome measures included hospital-acquired pressure ulcers (HAPUs) and patient falls. The unit of analysis was the patient care unit, and the final sample included 900 units of 5 adult unit types in 160 hospitals in the U.S. Multilevel logistic and Poisson regressions were used to estimate the relationship between collaboration and patient outcomes. All models were controlled for hospital and unit characteristics, and clustering of units within hospitals was considered. Results: On average, units had 26 patients with HAPUs per 1000 patients and 3 patient falls per 1000 patient days. Critical care units had the highest HAPU rate (50/1000 patients) and the lowest fall rate (1/1000 patient days). A one-unit increase in the nurse-nurse interaction scale score led to 31% decrease in the odds of having a HAPU (OR, 0.69; 95% CI, 0.56–0.82) and 8% lower patient fall rate (IRR, 0.92; 95% CI, 0.87–0.98) on a nursing unit. A one-unit increase in the nurse-physician interaction scale score was associated with 19% decrease in the odds of having a HAPU (OR, 0.81; 95% CI, 0.68–0.97) and 13% lower fall rates (IRR, 0.87; 95% CI, 0.82–0.93) on a unit. Conclusions: Both nurse-physician collaboration and nurse-nurse collaboration were significantly associated with patient safety outcomes. Findings from this study suggest that improving collaboration among healthcare providers should be considered as an important strategy for promoting patient safety and both interdisciplinary and intradisciplinary collaboration are critical for achieving better patient outcomes.
Interactive effects of sleep duration and morning/evening preference on cardiovascular risk factors
Patterson, F., Malone, S. K., Grandner, M. A., Lozano, A., Perkett, M., & Hanlon, A. (2018). European Journal of Public Health, 28(1), 155-161. 10.1093/eurpub/ckx029
Abstract
Background Sleep duration and morningness/eveningness (circadian preference) have separately been associated with cardiovascular risk factors (i.e. tobacco use, physical inactivity). Interactive effects are plausible, resulting from combinations of sleep homeostatic and circadian influences. These have not been examined in a population sample. Methods Multivariable regression models were used to test the associations between combinations of sleep duration (short [≤6 h], adequate [7-8 h], long [≥9 h]) and morning/evening preference (morning, somewhat morning, somewhat evening, evening) with the cardiovascular risk factors of tobacco use, physical inactivity, high sedentary behaviour, obesity/overweight and eating fewer than 5 daily servings of fruit and vegetables, in a cross-sectional sample of 439 933 adults enrolled in the United Kingdom Biobank project. Results Participants were 56% female, 95% white and mean age was 56.5 (SD = 8.1) years. Compared with adequate sleep with morning preference (referent group), long sleep with evening preference had a relative odds of 3.23 for tobacco use, a 2.02-fold relative odds of not meeting physical activity recommendations, a 2.19-fold relative odds of high screen-based sedentary behaviour, a 1.47-fold relative odds of being obese/overweight and a 1.62-fold relative odds of <5 fruit and vegetable daily servings. Adequate sleep with either morning or somewhat morning preference was associated with a lower prevalence and odds for all cardiovascular risk behaviours except fruit and vegetable intake. Conclusions Long sleepers with evening preference may be a sleep phenotype at high cardiovascular risk. Further work is needed to examine these relationships longitudinally and to assess the effects of chronotherapeutic interventions on cardiovascular risk behaviours.
Intercepting behavioral health problems
Hallas, D. (2018). In Behavioral Pediatric Healthcare for Nurse Practitioners: A conceptual model (1–, pp. 3-16). Springer Publishing Company. 10.1891/9780826116819.0001
Abstract
The overarching goal for providing behavioral and mental health services in pediatric primary care settings is to provide immediate and effective services to children, adolescents, and their families to change the course from potential adverse behavioral health outcomes to supportive positive directions in growth and developmental behavioral health. This textbook provides an analysis of evidence-based behavioral health practices to foster growth and developmental behavioral health through early behavioral health screenings and assessments with the goal of intercepting behavioral development and characteristics that are not within the “norm” of pediatric and adolescent development. The conceptual model for Intercepting Behavioral Health problems focuses on identifying the very earliest presentation of even one symptom that may lead to a behavioral health problem and immediately beginning the process for intercepting the potential problem with evidence-based treatments. Pediatric primary care providers play a unique role in caring for children with behavioral health problems.
Interdisciplinary Collaborations in Global Health Research
Kurth, A., Squires, A., Shedlin, M., & Kiarie, J. (2018). In Global Health Nursing in the 21st Century (1–). Springer Publishing Company. 10.1891/9780826118721.0031
Knowing something versus feeling different: the effects and non-effects of genetic ancestry on racial identity
Shim, J. K., Rab Alam, S., & Aouizerat, B. E. (2018). New Genetics and Society, 37(1), 44-66. 10.1080/14636778.2018.1430560
Abstract
Since the completion of the Human Genome Project, there have been pitched debates about its implications and the research it enables. One prominent thread of concern focuses on the role of post-genomic science on technically enabling and generating interest in genetic ancestry testing (GAT). Critical analyses of GAT have pointed to multiple issues, raising the alarm on consumers’ experiences with such technologies. This paper describes the results of a pilot study in which we tracked women’s experiences receiving their genetic ancestry results, and their understandings of, reactions to, and valuing of this information over time. Overwhelmingly, our participants reported a curious combination of anticipation and satisfaction yet no discernable impact on their sense of self or racial identity. We elaborate on the effects and non-effects of GAT for the women in our study, and how we make sense of their simultaneous experiences of ‘knowing something’ but not ‘feeling different.’.
Knowledge and behaviours related to oral health among underserved older adults
Shedlin, M. G., Birdsall, S. B., & Northridge, M. E. (2018). Gerodontology, 35(4), 339-349. 10.1111/ger.12367
Abstract
Objective: To examine the mouth and body knowledge, beliefs and behaviours of Dominican, Puerto Rican and African American older adults, and their relationships to oral and general health and health care. Background: In his seminal framework, Handwerker posited that the norms, attitudes and behaviours related to the experience of disease and treatment reflect where patients live and have lived and are seeking and have sought care, along with their webs of social and health relations. This framework guides the analysis for the present study, wherein qualitative data are used to understand mouth and body knowledge, beliefs and behaviours among racial/ethnic minority older adults, ie, why individuals do what they do and what it means to them. Materials and methods: Focus groups were conducted in Spanish or English with 194 racial/ethnic minority older adults living in northern Manhattan who participated in one of 24 focus group sessions about improving oral health. All groups were digitally audio-recorded, transcribed and translated into English from Spanish, where apt. Analysis involved the classification of evidence from all datasets, organised to identify patterns and relationships. Results: Four themes were manifest in the data regarding cultural understandings of the mouth, the body and health: (a) the ageing mouth and its components; (b) the mouth in relation to the body, health and disease; (c) social meanings of the mouth; and (d) care of the ageing mouth. Conclusion: Underserved older adults from diverse cultural backgrounds understand the importance of their mouths to both their overall health and social lives.
Machine learning for detection of lymphedema among breast cancer survivors
Fu, M., Wang, Y., LI, C., Qiu, Z., Axelrod, D., Guth, A. A., Scagliola, J., Conley, Y. P., Aouizerat, B., Qiu, J. M., Yu, G., Van Cleave, J., Haber, J., & Cheung, Y. K. (2018). MHealth, 4. 10.21037/mhealth.2018.04.02
Abstract
Background: In the digital era when mHealth has emerged as an important venue for health care, the application of computer science, such as machine learning, has proven to be a powerful tool for health care in detecting or predicting various medical conditions by providing improved accuracy over conventional statistical or expert-based systems. Symptoms are often indicators for abnormal changes in body functioning due to illness or side effects from medical treatment. Real-time symptom report refers to the report of symptoms that patients are experiencing at the time of reporting. The use of machine learning integrating real-time patient-centered symptom report and real-time clinical analytics to develop real-time precision prediction may improve early detection of lymphedema and long term clinical decision support for breast cancer survivors who face lifelong risk of lymphedema. Lymphedema, which is associated with more than 20 distressing symptoms, is one of the most distressing and dreaded late adverse effects from breast cancer treatment. Currently there is no cure for lymphedema, but early detection can help patients to receive timely intervention to effectively manage lymphedema. Because lymphedema can occur immediately after cancer surgery or as late as 20 years after surgery, real-time detection of lymphedema using machine learning is paramount to achieve timely detection that can reduce the risk of lymphedema progression to chronic or severe stages. This study appraised the accuracy, sensitivity, and specificity to detect lymphedema status using machine learning algorithms based on real-time symptom report.Methods: A web-based study was conducted to collect patients' real-time report of symptoms using a mHealth system. Data regarding demographic and clinical information, lymphedema status, and symptom features were collected. A total of 355 patients from 45 states in the US completed the study. Statistical and machine learning procedures were performed for data analysis. The performance of five renowned classification algorithms of machine learning were compared: Decision Tree of C4.5, Decision Tree of C5.0, gradient boosting model (GBM), artificial neural network (ANN), and support vector machine (SVM). Each classification algorithm has certain user-definable hyper parameters. Five-fold cross validation was used to optimize these hyper parameters and to choose the parameters that led to the highest average cross validation accuracy.Results: Using machine leaning procedures comparing different algorithms is feasible. The ANN achieved the best performance for detecting lymphedema with accuracy of 93.75%, sensitivity of 95.65%, and specificity of 91.03%.Conclusions: A well-trained ANN classifier using real-time symptom report can provide highly accurate detection of lymphedema. Such detection accuracy is significantly higher than that achievable by current and often used clinical methods such as bio-impedance analysis. Use of a well-trained classification algorithm to detect lymphedema based on symptom features is a highly promising tool that may improve lymphedema outcomes.
Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality
Zhang, X., Hu, Y., Aouizerat, B. E., Peng, G., Marconi, V. C., Corley, M. J., Hulgan, T., Bryant, K. J., Zhao, H., Krystal, J. H., Justice, A. C., & Xu, K. (2018). Clinical Epigenetics, 10(1). 10.1186/s13148-018-0591-z
Abstract
Background: The effects of tobacco smoking on epigenome-wide methylation signatures in white blood cells (WBCs) collected from persons living with HIV may have important implications for their immune-related outcomes, including frailty and mortality. The application of a machine learning approach to the analysis of CpG methylation in the epigenome enables the selection of phenotypically relevant features from high-dimensional data. Using this approach, we now report that a set of smoking-associated DNA-methylated CpGs predicts HIV prognosis and mortality in an HIV-positive veteran population. Results: We first identified 137 epigenome-wide significant CpGs for smoking in WBCs from 1137 HIV-positive individuals (p < 1.70E-07). To examine whether smoking-associated CpGs were predictive of HIV frailty and mortality, we applied ensemble-based machine learning to build a model in a training sample employing 408,583 CpGs. A set of 698 CpGs was selected and predictive of high HIV frailty in a testing sample [(area under curve (AUC) = 0.73, 95%CI 0.63~0.83)] and was replicated in an independent sample [(AUC = 0.78, 95%CI 0.73~0.83)]. We further found an association of a DNA methylation index constructed from the 698 CpGs that were associated with a 5-year survival rate [HR = 1.46; 95%CI 1.06~2.02, p = 0.02]. Interestingly, the 698 CpGs located on 445 genes were enriched on the integrin signaling pathway (p = 9.55E-05, false discovery rate = 0.036), which is responsible for the regulation of the cell cycle, differentiation, and adhesion. Conclusion: We demonstrated that smoking-associated DNA methylation features in white blood cells predict HIV infection-related clinical outcomes in a population living with HIV.
Macrocognition in the Healthcare Built Environment (mHCBE): A Focused Ethnographic Study of “Neighborhoods” in a Pediatric Intensive Care Unit
O’Hara, S., Klar, R. T., Patterson, E. S., Morris, N. S., Ascenzi, J., Fackler, J. C., & Perry, D. J. (2018). Health Environments Research and Design Journal, 11(2), 104-123. 10.1177/1937586717728484
Abstract
Objectives: The objectives of this research were to describe the interactions (formal and informal), in which macrocognitive functions occur and their location on a pediatric intensive care unit, to describe challenges and facilitators of macrocognition using space syntax constructs (openness, connectivity, and visibility), and to analyze the healthcare built environment (HCBE) using those constructs to explicate influences on macrocognition. Background: In high reliability, complex industries, macrocognition is an approach to develop new knowledge among interprofessional team members. Although macrocognitive functions have been analyzed in multiple healthcare settings, the effect of the HCBE on those functions has not been directly studied. The theoretical framework, “macrocognition in the healthcare built environment” (mHCBE) addresses this relationship. Method: A focused ethnographic study was conducted including observation and focus groups. Architectural drawing files used to create distance matrices and isovist field view analyses were compared to panoramic photographs and ethnographic data. Results: Neighborhoods comprised of corner configurations with maximized visibility enhanced team interactions as well as observation of patients, offering the greatest opportunity for informal situated macrocognitive interactions (SMIs). Conclusions: Results from this study support the intricate link between macrocognitive interactions and space syntax constructs within the HCBE. These findings help increase understanding of how use of the framework of Macrocognition in the HCBE can improve design and support adaptation of interprofessional team practices, maximizing macrocognitive interaction opportunities for patient, family, and team safety and quality.
Maternal dyslipidemia and risk for preterm birth
Smith, C. J., Baer, R. J., Oltman, S. P., Breheny, P. J., Bao, W., Robinson, J. G., Dagle, J. M., Liang, L., Feuer, S. K., Chambers, C. D., Jelliffe-Pawlowski, L. L., & Ryckman, K. K. (2018). PloS One, 13(12). 10.1371/journal.pone.0209579
Abstract
Maternal lipid profiles during pregnancy are associated with risk for preterm birth. This study investigates the association between maternal dyslipidemia and subsequent preterm birth among pregnant women in the state of California. Births were identified from California birth certificate and hospital discharge records from 2007–2012 (N = 2,865,987). Preterm birth was defined as <37 weeks completed gestation and dyslipidemia was defined by diagnostic codes. Subtypes of preterm birth were classified as preterm premature rupture of membranes (PPROM), spontaneous labor, and medically indicated, according to birth certificate data and diagnostic codes. The association between dyslipidemia and preterm birth was tested with logistic regression. Models were adjusted for maternal age at delivery, race/ethnicity, hypertension, pre-pregnancy body mass index, insurance type, and education. Maternal dyslipidemia was significantly associated with increased odds of preterm birth (adjusted OR: 1.49, 95%CI: 1.39, 1.59). This finding was consistent across all subtypes of preterm birth, including PPROM (adjusted OR: 1.54, 95%CI: 1.34, 1.76), spontaneous (adjusted OR: 1.51, 95%CI: 1.39, 1.65), and medically indicated (adjusted OR: 1.454, 95% CI: 1.282, 1.649). This study suggests that maternal dyslipidemia is associated with increased risk for all types of preterm birth.
Medication literacy and Somali older adults receiving home care
Miner, S., McDonald, M. V., & Squires, A. (2018). Home Healthcare Now, 36(5), 295-303. 10.1097/NHH.0000000000000673
Abstract
Medication literacy is the ability of individuals to access and understand medication information and then use that information to act and take their medication in a safe and appropriate way. The purpose of this study was to explore medication literacy in a group of Somali older adults and their families using qualitative secondary analysis. We conducted an analytic expansion of an existing qualitative study that explored the home healthcare perceptions of Somali older adults and their families. Qualitative data collected from 14 Somali families about home healthcare were reviewed and analyzed for material related to medication literacy. Data analysis revealed a number of important findings related to medication literacy and resulted in the discovery of four themes: Medication literacy is needed among Somali older adults and their families, Using home healthcare (HHC) to improve medication literacy, Better communication is essential to improving medication literacy, and Medication literacy is an intersecting family and social issue. The results of this study indicate that HHC has a role to play in improving the health and medication literacy of these families. They also highlight the need to further explore what techniques, tools, and/or supports HHC professionals need to care for non-English speaking populations. Future research needs to address how to meet the needs of diverse and vulnerable patients like Somali older adults, and how best to prepare HHC providers to do this.
Men's health awareness: Change through education
Newland, J. A. (2018). Nurse Practitioner, 43(6), 7. 10.1097/01.NPR.0000532768.21875.4b
Meta-Synthesis on Migraine Management
Minen, M. T., Anglin, C., Boubour, A., Squires, A., & Herrmann, L. (2018). Headache, 58(1), 22-44. 10.1111/head.13212
Abstract
Background: Migraine is one of the top 10 most disabling conditions among adults worldwide. Most migraine research is quantitative and indicates concerns about medication adherence, stigma, and more. Qualitative studies might reveal an improved understanding of migraine patients’ perspectives regarding migraine treatment. Objective: The aim of this study was to synthesize the qualitative research on migraine patients’ perspectives regarding migraine treatment to (a) identify common patterns across various types of migraine treatment studies and (b) inform future research. Methods: A systematic search for qualitative studies in the HA (HA) literature was conducted in Medline (PubMed), PsycINFO, EMBASE, CINAHL, Web of Science, Joanna Briggs Institute EBP Database, and The Cochrane Library. Search terms (subject headings and keywords) were HA, HA disorders, migraine, qualitative studies, and qualitative research. Qualitative studies were systematically identified by using published qualitative search filters recommended by The InterTASC Information Specialists’ Sub-Group (ISSG). The search was limited to English only, peer reviewed publications, and studies published between 1996 and 2016. For screening, additional inclusion criteria were (1) adult migraine patients; (2) must mention treatment in the title or study design of the abstract. Ten studies met the inclusion criteria. The Critical Appraisal Skills Program tool was applied to appraise study quality. Thematic analysis produced the codes and themes. Two authors read articles separately and individually created codes. Code lists were synthesized and themes emerged iteratively from the process. Results: Study sample sizes ranged from 10 to 33 participants, with our findings representing 161 participants. Data were collected either using interviews or focus groups. The more common methodologies were grounded theory and phenomenology. Few (3) studies described the number of headache (HA) days for inclusion in the study. Eight out of 10 used International Classification of Headache Disorders (ICHD) criteria. Our synthesis produced five major themes. The first theme was “Migraine patients’ difficulties with health care utilization,” and it included issues surrounding the cost of migraine treatment (seeing providers and prescription medications). The second theme was “Migraine patients’ perceived relationships with their providers,” which included the role and relationship with the provider, as well as trust in the provider and the providers’ knowledge in managing HAs. The third theme was “Thoughts about the various migraine treatments.” It was based on patients’ comments indicating an aversion to prescription medications, the use of non-pharmacological interventions for treatment, behavioral modification as a form of treatment, and the need for additional treatment options. The fourth and fifth themes were “Understanding diagnosis/triggers” and “Societal implications,” respectively. The latter theme included feelings of not being taken seriously and issues surrounding quality of life. Discussion: The metasynthesis revealed several key commonalities regarding patients’ perspectives on migraine treatment and identified new areas for research using a qualitative approach. Researchers conducting qualitative research with patients experiencing migraines might consider using and reporting more of the inclusion and exclusion criteria commonly used in migraine research, for example, reporting whether the ICHD criteria were used and the number of HA days for patients to be in a study. Future studies might be done to determine how the role of allied health care providers, for example, pharmacists, physical therapists, and psychologists, might be expanded to help with migraine treatment and ultimately to improve patient outcomes.
Migration and cognitive function: a conceptual framework for Global Health Research
Xu, H., Vorderstrasse, A. A., McConnell, E. S., Dupre, M. E., Østbye, T., & Wu, B. (2018). Global Health Research and Policy, 3(1). 10.1186/s41256-018-0088-5
Abstract
Background: Migration is a fundamental demographic process that has been observed globally. It is suggested that migration is an issue of global health importance that can have an immediate and lasting impact on an individual’s health and well-being. There is now an increasing body of evidence linking migration with cognitive function in older adults. In this paper, we synthesized the current evidence to develop a general conceptual framework to understand the factors contributing to the association between migration and cognitive function. Methods: A comprehensive review of the literature was conducted on the associations between migration and cognition among middle-aged and older adults. Results: Five potential mechanisms were identified from the literature: 1) socioeconomic status—including education, occupation, and income; 2) psychosocial factors—including social networks, social support, social stressors, and discrimination; 3) behavioral factors—including smoking, drinking, and health service utilization; 4) physical and psychological health status—including chronic conditions, physical function, and depression; and 5) environmental factors—including both physical and social environment. Several underlying factors were also identified—including early-life conditions, gender, and genetic factors. Conclusions: The factors linking migration and cognitive function are multidimensional and complex. This conceptual framework highlights potential implications for global health policies and planning on healthy aging and migrant health. Additional studies are needed to further examine these mechanisms to extend and refine our general conceptual framework.
Minority stress and leukocyte gene expression in sexual minority men living with treated HIV infection
Flentje, A., Kober, K. M., Carrico, A. W., Neilands, T. B., Flowers, E., Heck, N. C., & Aouizerat, B. E. (2018). Brain, Behavior, and Immunity, 70, 335-345. 10.1016/j.bbi.2018.03.016
Abstract
Sexual minority (i.e., non-heterosexual) individuals experience poorer mental and physical health, accounted for in part by the additional burden of sexual minority stress occurring from being situated in a culture favoring heteronormativity. Informed by previous research, the purpose of this study was to identify the relationship between sexual minority stress and leukocyte gene expression related to inflammation, cancer, immune function, and cardiovascular function. Sexual minority men living with HIV who were on anti-retroviral medication, had viral load < 200 copies/mL, and had biologically confirmed, recent methamphetamine use completed minority stress measures and submitted blood samples for RNA sequencing on leukocytes. Differential gene expression and pathway analyses were conducted comparing those with clinically elevated minority stress (n = 18) and those who did not meet the clinical cutoff (n = 20), covarying reactive urine toxicology results for very recent stimulant use. In total, 90 differentially expressed genes and 138 gene set pathways evidencing 2-directional perturbation were observed at false discovery rate (FDR) < 0.10. Of these, 41 of the differentially expressed genes and 35 of the 2-directionally perturbed pathways were identified as functionally related to hypothesized mechanisms of inflammation, cancer, immune function, and cardiovascular function. The neuroactive-ligand receptor pathway (implicated in cancer development) was identified using signaling pathway impact analysis. Our results suggest several potential biological pathways for future work investigating the relationship between sexual minority stress and health.
Moving Beyond Age: An Exploratory Qualitative Study on the Context of Young African American Men and Women’s Sexual Debut
Lanier, Y., Stewart, J. M., Schensul, J. J., & Guthrie, B. J. (2018). Journal of Racial and Ethnic Health Disparities, 5(2), 261-270. 10.1007/s40615-017-0366-9
Abstract
African American youth continue to be disproportionately affected by HIV. Early sexual debut has been identified as a major determinant of HIV risk. However, emerging research suggests that the overarching context in which first sex occurs may have greater implications for sexual health than simply age alone. The purpose of this exploratory, qualitative study was to better understand the broader context of African Americans’ sexual debut. In-depth, semi-structured interviews were conducted with 10 African American men and women aged 18–24 years. Thematic analysis was used to analyze the data. The mean age at sexual debut for the sample was 15.4 (SD = 3.3), and youth framed their sexual debut as positive (50%), negative (30%), and both positive and negative (20%). The majority of youth initiated pre-sex conversations with their partners to gauge potential interest in engaging in sexual activity, and all youth utilized at least one HIV/sexually transmitted infection and pregnancy prevention method. However, most youth failed to talk to their partners prior to sex about their past sexual histories and what the experience meant for their relationship. Key differences emerged between youth who framed the experience as positive and those who framed the experience as negative or both positive and negative in terms of their motivations for initiating sex (i.e., readiness to initiate sex, pressure, and emotionally safety) and post-sex emotions (i.e., remorse and contentment). Findings provide further support for examining the broader sexual context of African American’s sexual debut. A more comprehensive understanding of sexual debut will aid in the development and tailoring of sexual risk reduction programs targeting African American youth.
Moving Beyond Pain as the Fifth Vital Sign and Patient Satisfaction Scores to Improve Pain Care in the 21st Century
Scher, C., Meador, L., Van Cleave, J. H., & Reid, M. C. (2018). Pain Management Nursing, 19(2), 125-129. 10.1016/j.pmn.2017.10.010
Abstract
In an attempt to address the issue of undertreated pain, the Pain as the Fifth Vital Sign (P5VS) Initiative was established to improve the quality of pain care across clinical settings. This initiative included policy efforts such as mandatory pain screening and the implementation of pain-related questions on patient satisfaction surveys. These policies have failed to enhance the treatment of pain and may have unintentionally contributed, in part, to the opioid epidemic. To assess pain more effectively, an inter-professional team approach using multi-dimensional pain assessment tools is needed. The inter-professional team can use these multi-dimensional tools to conduct comprehensive assessments to measure aspects of the pain experience (e.g., psychological, spiritual and socio-emotional pain; impact on daily functioning) beyond its sensory component and establish realistic goals that align with patients' needs. To implement multi-dimensional pain assessments in busy clinical practices, nurses will need to play a central role. Nurses can work to ensure that patients complete the questionnaires prior to the visit. Nurses can also take the lead in the use of new technologies in the form of tablets, smart phones, and mobile apps to facilitate collecting patient-level data in the home or in a waiting room before their visits.
National Nurses Week 2018: Inspire, innovate, influence
Newland, J. A. (2018). Nurse Practitioner, 43(5). 10.1097/01.NPR.0000531922.30258.b2
Neurogenic dysphagia with undigested macaroni and megaesophagus in familial dysautonomia
Palma, J. A., Spalink, C., Barnes, E. P., Norcliffe-Kaufmann, L., & Kaufmann, H. (2018, February 1). In Clinical Autonomic Research (Vols. 28, Issue 1, pp. 125-126). 10.1007/s10286-017-0487-6
Nurse practitioners: past, present, and future.
Cayo, S., Gilles, S., & Godwin, A. (2018). NBNA News, 50-52.
Nursing Care of a Family in Crisis: Maltreatment and Violence in the Family.
Quinones, S. (2018). In In Pillitteri (Flagg). Maternal & Child Health Nursing: Care of the Childbearing & Childrearing Family (8th eds., 1–).
Nursing Care of a Family when a Child has an Unintentional Injury
Quinones, S. (2018). In In Pillitteri (Flagg). Maternal & Child Health Nursing: Care of the Childbearing & Childrearing Family (8th eds., 1–).
Nursing Humanities: Teaching for a Sense of Salience
Lim, F., & Marsaglia, M. J. (2018). Nursing Education Perspectives, 39(2), 121-122. 10.1097/01.NEP.0000000000000184
Abstract
Reports have indicated that nursing programs in the United States are not generally effective in teaching nursing science, natural science, the social sciences, and the humanities. The value of the lifelong study of humanities for nurses is the invitation for contemplation on the human experience so we can make informed moral, spiritual, and intellectual sense of the world. In essence, when we understand, we become more empathetic. This article adds to the call for teaching for a sense of salience in nursing through the meaningful synthesis of humanities in baccalaureate education.