Daniel David

Faculty

Daniel David headshot

Daniel David

PhD RN

Assistant Professor

1 212 992 5930

433 First Ave
New York, NY 10010
United States

Accepting PhD students

Daniel David, RN, PhD, is an assistant professor at NYU Rory Meyers College of Nursing and National Palliative Care Center Kornfeld Scholar. His research investigates older adults and their informal caregivers in the context of serious illness. He is particularly interested in technology-based interventions that improve caregiving, communication, palliative care, and advance care planning.

David is the principal investigator of the PC-CRAFT Assisted Living Project (Palliative Care – Connecting Residents And Family through Technology), which uses video technology to support palliative care consultation between providers, residents of assisted living, and their informal caregivers.

Prior to joining the faculty at NYU, David was an adjunct assistant professor in the Department of Community Health Systems at the University of California, San Francisco (UCSF) School of Nursing and a postdoctoral fellow in the VA Quality Scholar Program in the UCSF Division of Geriatrics.

David received his PhD in nursing from Northeastern University, MS from the University of Colorado, and BSN from the University of Virginia.

PhD - Northeastern University
BSN - University of Virginia
MS - University of Colorado

Gerontology
Palliative care

American Geriatrics Society
Gerontological Society of America
Hospice and Palliative Nurses Association
Palliative Care Research Cooperative
Sigma Theta Tau

Junior Investigator, Palliative Care Research Consortium (2018)
VA Quality Scholar, VA Medical Center, San Francisco (2018)
Scholarship, End of Life Nursing Education Consortium (2017)
Sigma Theta Tau, Scholar Research Award, Northeastern University (2016)
Kaneb Foundation Research Award, Regis College (2015)
Scholar, Summer Genetics Institute, NINR, National Institute of Health (2014)
Scholar, Jonas Center for Nursing Excellence (2014)
Sigma Theta Tau, Rising Star Award, Northeastern University (2013)
Sigma Theta Tau, Beta Kappa (2004), Gamma Epsilon Chapter (2013)
Distinguished Nursing Student Award, University of Virginia (2005)
Raven Society, University of Virginia (2005)

6-Hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor

Bowenkamp, K. E., David, D., Lapchak, P. L., Henry, M. A., Granholm, A. C., Hoffer, B. J., & Mahalik, T. J. (1996). Experimental Brain Research, 111(1), 1-7.
Abstract
Abstract
Intraparenchymal injections of the neurotoxin 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle in rats destroys the dopaminergic neurons in the pars compacta of the substantia nigra. In other transmitter systems it has been found that axotomy or neurotoxin exposure produces an initial loss of neurotransmitter phenotype, with cell death occurring over a much slower time course. To determine whether this also occurs in dopamine neurons after 6-OHDA, two approaches were utilized. First, the effect of injections of 6-OHDA into the medial forebrain bundle on nigral dopaminergic neurons was studied using combined fluorogold and immunocytochemical labeling. Four weeks after the 6-OHDA injection, there was an 85% reduction in the number of tyrosine hydroxylase (TH)-immunoreactive cells on the lesioned side. In contrast, there was only a 50% reduction in the number of fluorogold-labeled cells on the lesioned side. Second, the time course of the rescue of dopaminergic neurons after 6-OHDA by glial cell line-derived neurotrophic factor (GDNF) was determined using TH immunocytochemistry. Greater numbers of dopamine neurons were rescued 9 weeks after GDNF compared with counts made 5 weeks after GDNF. Taken together, these results suggest loss of dopaminergic phenotype is greater than cell loss following 6-OHDA injections, and that GDNF restores the phenotype of affected cells.